Open Chromatin Profiling Identifies Functional Noncoding Risk Variants In Human Ipsc Model of Psychiatric Disorders
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DOI: 10.1016/j.euroneuro.2017.06.122
Abstract: Abstract Most disease variants lie within poorly-annotated noncoding parts of the genome, and their functional interpretation is challenging. To functionally assess the relevance of noncoding sequences in neuropsychiatric disorders, we hypothesized that disease-relevant noncoding sequences… read more here.
Keywords: risk; noncoding; open chromatin; human ipsc ... See more keywords