Nonhuman Primate Models for Studies of AIDS Virus Persistence During Suppressive Combination Antiretroviral Therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2017_73
Abstract: Nonhuman primate (NHP) models of AIDS represent a potentially powerful component of the effort to understand in vivo sources of AIDS virus that persist in the setting of suppressive combination antiretroviral therapy (cART) and to… read more here.
Keywords: antiretroviral therapy; combination antiretroviral; suppressive combination; nonhuman primate ... See more keywords
Optimization of Differentiation of Nonhuman Primate Pluripotent Cells Using a Combinatorial Approach.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9007-8_14
Abstract: The directed differentiation of pluripotent stem cells to a desired lineage often involves complex and lengthy protocols. In order to study the requirements for differentiation in a systematic way, we present here methodology for an… read more here.
Keywords: pluripotent; differentiation nonhuman; differentiation; nonhuman primate ... See more keywords
Nonhuman Primate Optogenetics: Current Status and Future Prospects.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-15-8763-4_22
Abstract: Nonhuman primates (NHPs) have widely and crucially been utilized as model animals for understanding various higher brain functions and neurological disorders since their behavioral actions mimic both normal and disease states in humans. To know… read more here.
Keywords: primate optogenetics; status future; future prospects; current status ... See more keywords
The role of nonhuman primate models in the development of cell-based therapies for Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-017-1708-9
Abstract: Through the course of over three decades, nonhuman primate (NHP) studies on cell-based therapies (CBTs) for Parkinson’s disease (PD) have provided insight into the feasibility, safety and efficacy of the approach, methods of cell collection… read more here.
Keywords: based therapies; cell based; role; nonhuman primate ... See more keywords
Advances in nonhuman primate models of autism: Integrating neuroscience and behavior
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2017.07.021
Abstract: Given the prevalence and societal impact of autism spectrum disorders (ASD), there is an urgent need to develop innovative preventative strategies and treatments to reduce the alarming number of cases and improve core symptoms for… read more here.
Keywords: primate models; models autism; autism integrating; advances nonhuman ... See more keywords
Nonhuman primate models in the study of spaceflight stressors: Past contributions and future directions.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences in space research"
DOI: 10.1016/j.lssr.2021.03.008
Abstract: Studies in rodents suggest that exposure to distinct spaceflight stressors (e.g., space radiation, isolation/confinement, microgravity) may have a profound impact on an astronaut's ability to perform both simple and complex tasks related to neurocognitive performance,… read more here.
Keywords: spaceflight stressors; nonhuman primate; past contributions; research ... See more keywords
Effects of oral domoic acid exposure on maternal reproduction and infant birth characteristics in a preclinical nonhuman primate model.
Sign Up to like & getrecommendations! Published in 2019 at "Neurotoxicology and teratology"
DOI: 10.1016/j.ntt.2019.01.001
Abstract: Domoic Acid (DA) is a naturally-occurring excitotoxin, produced by marine algae, which can bioaccumulate in shellfish and finfish. The consumption of seafood contaminated with DA is associated with gastrointestinal illness that, in the case of… read more here.
Keywords: primate model; birth; exposure; domoic acid ... See more keywords
Estradiol Treatment in a Nonhuman Primate Model of Menopause Preserves Affective Reactivity
Sign Up to like & getrecommendations! Published in 2018 at "Behavioral Neuroscience"
DOI: 10.1037/bne0000253
Abstract: Human affective life changes with age, becoming more positive and less negative in later life. This change occurs even as aging leads to declines in health and cognitive outcomes. Despite these well-documented effects in humans,… read more here.
Keywords: affective reactivity; model; reactivity; threat ... See more keywords
Failed remyelination of the nonhuman primate optic nerve leads to axon degeneration, retinal damages, and visual dysfunction
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2115973119
Abstract: Significance Promotion of remyelination has become a new therapeutic avenue to prevent neuronal degeneration and promote recovery in white matter diseases, such as multiple sclerosis (MS). To date most of these strategies have been developed… read more here.
Keywords: nonhuman primate; degeneration; remyelination; failed remyelination ... See more keywords
Regional strain response of an anatomically accurate nonhuman primate finite element brain model under frontal impact
Sign Up to like & getrecommendations! Published in 2022 at "Traffic Injury Prevention"
DOI: 10.1080/15389588.2022.2124813
Abstract: are those of the authors and should not be construed as an official Department of the Army or Medical College of Wisconsin position, policy, or decision, unless so designated by other official documentation. Citation of… read more here.
Keywords: nonhuman primate; anatomically accurate; regional strain; response anatomically ... See more keywords
Preparation of Nonhuman Primate Eyes for Histological Evaluation After Retinal Gene Transfer.
Sign Up to like & getrecommendations! Published in 2018 at "Human gene therapy methods"
DOI: 10.1089/hgtb.2018.045
Abstract: To evaluate gene therapy for retinal disorders, appropriate models of the human eye are needed. Nonhuman primate eyes offer significant advantages over rodent eyes. However, current preparation methods have limitations. Here, a protocol is described… read more here.
Keywords: primate eyes; evaluation; nonhuman primate; gene transfer ... See more keywords