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   Articles with "nonlinear mixed" as a keyword



Influence of Renal Function on Phosphoramide Mustard Exposure: A Nonlinear Mixed‐Effects Analysis

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recommendations! Published in 2022 at "Journal of Clinical Pharmacology"

DOI: 10.1002/jcph.2144

Abstract: Phosphoramide mustard (PM) is the final cytotoxic metabolite formed from the parent compound cyclophosphamide through a complex metabolic pathway, primarily through hepatic metabolism. Little is known about the effect of renal elimination on the disposition… read more here.

Keywords: mixed effects; function; phosphoramide mustard; renal function ... See more keywords
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Numerical analysis of nonlinear mixed convective MHD chemically reacting flow of Prandtl–Eyring nanofluids in the presence of activation energy and Joule heating

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recommendations! Published in 2020 at "Journal of Thermal Analysis and Calorimetry"

DOI: 10.1007/s10973-020-09574-2

Abstract: The aim of the study is to explore nonlinear mixed convection flow of nanomaterials (Prandtl–Eyring nanoliquid) with activation energy. Analysis of cross-diffusion (Soret and Dufour) impacts is addressed. Features of nanoliquid are analysed with thermophoresis… read more here.

Keywords: activation energy; analysis; prandtl eyring; nonlinear mixed ... See more keywords

Mixture of multivariate t nonlinear mixed models for multiple longitudinal data with heterogeneity and missing values

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recommendations! Published in 2019 at "TEST"

DOI: 10.1007/s11749-018-0612-4

Abstract: The multivariate t nonlinear mixed-effects model (MtNLMM) has been shown to be effective for analyzing multi-outcome longitudinal data following nonlinear growth patterns with fat-tailed noises or potential outliers. This paper considers the problem of clustering… read more here.

Keywords: longitudinal data; missing values; mixture multivariate; multivariate nonlinear ... See more keywords

A generalized nonlinear mixed-effects height to crown base model for Mongolian oak in northeast China

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recommendations! Published in 2017 at "Forest Ecology and Management"

DOI: 10.1016/j.foreco.2016.09.012

Abstract: Abstract Tree height to crown base (HCB) is an important variable commonly included as one of the predictors in growth and yield models that are the decision-support tools in forest management. In this study, we… read more here.

Keywords: sample; mixed effects; model; random effects ... See more keywords

Nonlinear Mixed Effects Modeling of Deterministic and Stochastic Dynamical Systems in Wolfram Mathematica

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recommendations! Published in 2021 at "IFAC-PapersOnLine"

DOI: 10.1016/j.ifacol.2021.08.394

Abstract: Abstract Nonlinear mixed effects (NLME) modeling is a powerful tool to analyze time-series data from several individual entities in an experiment. In this paper, we give a brief overview of a package for NLME modeling… read more here.

Keywords: effects modeling; modeling deterministic; mixed effects; dynamical systems ... See more keywords

The Impact of Functional Form Complexity on Model Overfitting for Nonlinear Mixed-Effects Models.

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recommendations! Published in 2022 at "Multivariate behavioral research"

DOI: 10.1080/00273171.2022.2119360

Abstract: Nonlinear mixed-effects models (NLMEMs) allow researchers to model curvilinear patterns of growth, but there is ambiguity as to what functional form the data follow. Often, researchers fit multiple nonlinear functions to data and use model… read more here.

Keywords: mixed effects; functional form; model; nonlinear mixed ... See more keywords

An investigation to improve a nonlinear mixed-effects approach for EC50 estimation based on multi-donor dose-response data.

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recommendations! Published in 2024 at "Journal of biopharmaceutical statistics"

DOI: 10.1080/10543406.2024.2421424

Abstract: Dose-response relationships are important in assessing the efficacy and potency of compounds, which can usually be characterized by a 4-parameter logistic (4-PL) model estimating EC50, slope factor, lower asymptote, and upper asymptote. EC50, the concentration… read more here.

Keywords: effects approach; nonlinear mixed; mixed effects; dose response ... See more keywords

Comparison of classical tumour growth models for patient derived and cell-line derived xenografts using the nonlinear mixed-effects framework

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recommendations! Published in 2022 at "Journal of Biological Dynamics"

DOI: 10.1080/17513758.2022.2061615

Abstract: In this study we compare seven mathematical models of tumour growth using nonlinear mixed-effects which allows for a simultaneous fitting of multiple data and an estimation of both mean behaviour and variability. This is performed… read more here.

Keywords: mixed effects; tumour growth; growth; using nonlinear ... See more keywords

Richards's equation and nonlinear mixed models applied to avian growth: why use them?

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recommendations! Published in 2019 at "Journal of Avian Biology"

DOI: 10.1111/jav.01864

Abstract: Postnatal growth is an important life‐history trait that varies widely across avian species, and several equations with a sigmoidal shape have been used to model it. Classical three‐parameter models have an inflection point fixed at… read more here.

Keywords: nonlinear mixed; growth; mixed models; richards equation ... See more keywords

Boundary Value Problems of Nonlinear Mixed-Type Fractional Differential Equations

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recommendations! Published in 2021 at "Journal of Mathematics"

DOI: 10.1155/2021/6692592

Abstract: In this paper, by means of a fixed point theorem for monotone decreasing operators on a cone, we discuss the existence of positive solutions for boundary value problems of nonlinear fractional singular differential equation. The… read more here.

Keywords: problems nonlinear; mixed type; boundary value; nonlinear mixed ... See more keywords

More Prominent Nonlinear Mixed Selectivity in the Dorsolateral Prefrontal than Posterior Parietal Cortex

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recommendations! Published in 2022 at "eNeuro"

DOI: 10.1523/eneuro.0517-21.2022

Abstract: Abstract Neurons in the dorsolateral prefrontal cortex (dlPFC) and posterior parietal cortex (PPC) are activated by different cognitive tasks and respond differently to the same stimuli depending on task. The conjunctive representations of multiple tasks… read more here.

Keywords: dorsolateral prefrontal; parietal cortex; cortex; selectivity ... See more keywords