Targeting the Nonmevalonate Pathway in Burkholderia cenocepacia Increases Susceptibility to Certain β-Lactam Antibiotics
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DOI: 10.1128/aac.02607-17
Abstract: ABSTRACT The nonmevalonate pathway is the sole pathway for isoprenoid biosynthesis in Burkholderia cenocepacia and is possibly a novel target for the development of antibacterial chemotherapy. The goals of the present study were to evaluate… read more here.
Keywords: cenocepacia; susceptibility; lactam antibiotics; burkholderia cenocepacia ... See more keywords
The Nonmevalonate Pathway of Isoprenoid Biosynthesis Supports Anaerobic Growth of Listeria monocytogenes
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DOI: 10.1128/iai.00788-19
Abstract: Isoprenoids are an essential and diverse class of molecules, present in all forms of life, that are synthesized from an essential common precursor derived from either the mevalonate pathway or the nonmevalonate pathway. Most bacteria… read more here.
Keywords: growth; listeria monocytogenes; mevalonate pathway; nonmevalonate pathway ... See more keywords