Nonparametric overdose control with late-onset toxicity in phase I clinical trials.
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DOI: 10.1093/biostatistics/kxw038
Abstract: Under the framework of Bayesian model selection, we propose a nonparametric overdose control (NOC) design for dose finding in phase I clinical trials. Each dose assignment is guided via a feasibility bound, which thereby can… read more here.
Keywords: late onset; nonparametric overdose; toxicity; overdose control ... See more keywords