Development of real‐time loop‐mediated isothermal amplification (RealAmp) method for sensitive and rapid detection of pathogenic and nonpathogenic Leptospira
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DOI: 10.1111/lam.13108
Abstract: Leptospirosis is a zoonotic disease that is spread through water contaminated with the spirochete Leptospira. In our study, RealAmp (real‐time loop‐mediated isothermal amplification) was developed to distinguish between pathogenic and nonpathogenic Leptospira spp. Melt curve… read more here.
Keywords: realamp; pathogenic nonpathogenic; nonpathogenic leptospira; real time ... See more keywords
Implication of the IL-10-Expression Signature in the Pathogenicity of Leptospira-Infected Macrophages
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DOI: 10.1128/spectrum.02595-21
Abstract: Activation of macrophages by Leptospira spp. infection is thought to be involved in the pathogenesis of leptospirosis. To evaluate the innate macrophage responses to Leptospira spp., specifically pathogenic versus nonpathogenic Leptospira spp., we characterized the… read more here.
Keywords: leptospira infected; infection; infected macrophages; nonpathogenic leptospira ... See more keywords