No-nonsense: insights into the functional interplay of nonsense-mediated mRNA decay factors
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Journal"
DOI: 10.1042/bcj20210556
Abstract: Nonsense-mediated messenger RNA decay (NMD) represents one of the main surveillance pathways used by eukaryotic cells to control the quality and abundance of mRNAs and to degrade viral RNA. NMD recognises mRNAs with a premature… read more here.
Keywords: nonsense; nonsense mediated; decay; mrna decay ... See more keywords
Nothing matters: the significance of the unidentifiable, the superficial and nonsense
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Qualitative Studies on Health and Well-being"
DOI: 10.1080/17482631.2019.1684780
Abstract: ABSTRACT Purpose: The aim of this study is to explore the ways in which “small things” may be of importance for people with mental health difficulties. Method: Empirical material from three different studies was reanalysed… read more here.
Keywords: unidentifiable superficial; nothing matters; small things; superficial nonsense ... See more keywords
Mechanisms and Regulation of Nonsense-Mediated mRNA Decay and Nonsense-Associated Altered Splicing in Lymphocytes
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21041335
Abstract: The presence of premature termination codons (PTCs) in transcripts is dangerous for the cell as they encode potentially deleterious truncated proteins that can act with dominant-negative or gain-of-function effects. To avoid the synthesis of these… read more here.
Keywords: decay; nonsense; mediated mrna; mrna decay ... See more keywords