Mechanisms and Regulation of Nonsense-Mediated mRNA Decay and Nonsense-Associated Altered Splicing in Lymphocytes
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DOI: 10.3390/ijms21041335
Abstract: The presence of premature termination codons (PTCs) in transcripts is dangerous for the cell as they encode potentially deleterious truncated proteins that can act with dominant-negative or gain-of-function effects. To avoid the synthesis of these… read more here.
Keywords: decay; nonsense; mediated mrna; mrna decay ... See more keywords