Elevated air quality index and fine particulate matter levels contribute to the poor prognosis and progression of nonsmall‐cell lung cancer: A cohort study combined with external validation
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4701
Abstract: Poor air quality can result in a variety of respiratory disorders. However, the air quality index (AQI) and the level of fine particulate matter (PM2.5) on the progression and prognosis of nonsmall‐cell lung cancer (NSCLC)… read more here.
Keywords: quality index; fine particulate; particulate matter; nonsmall cell ... See more keywords
Comparison between next‐generation sequencing and multiplex polymerase chain reaction assays for nonsmall‐cell lung cancer molecular diagnosis
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DOI: 10.1002/cam4.7162
Abstract: Genetic mutation detection has become an important step in nonsmall‐cell lung cancer (NSCLC) treatment because of the increasing number of drugs that target genomic rearrangements. A multiplex test that can detect multiple gene mutations prior… read more here.
Keywords: cancer; next generation; lung cancer; nonsmall cell ... See more keywords
Anlotinib in combination with docetaxel for advanced nonsmall cell lung cancer after failure of platinum‐based treatment: A phase 1/2 trial
Sign Up to like & getrecommendations! Published in 2025 at "Cancer"
DOI: 10.1002/cncr.35822
Abstract: The combination of anlotinib with chemotherapy has demonstrated encouraging efficacy in the treatment of nonsmall cell lung cancer (NSCLC). The objective of this phase 1/2 trial was to establish the maximum tolerated dose of anlotinib… read more here.
Keywords: cancer; phase trial; combination; lung cancer ... See more keywords
EGCG enhances antitumor effect of apatinib in nonsmall cell lung cancer by targeting VEGF signaling to inhibit glycolysis
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DOI: 10.1002/ddr.22239
Abstract: Nonsmall cell lung cancer (NSCLC), one of the most aggressive malignancies globally, is characterized by poor prognosis and limited life expectancy. Epigallocatechin‐3‐gallate (EGCG), a natural polyphenol found in green tea, has emerged as a promising… read more here.
Keywords: nonsmall cell; cell; effect apatinib; antitumor effect ... See more keywords
Repeat Thoracic Stereotactic Body Radiation Therapy (SBRT) for Nonsmall Cell Lung Cancer: Long-Term Outcomes, Toxicity, and Dosimetric Considerations
Sign Up to like & getrecommendations! Published in 2020 at "Advances in Radiation Oncology"
DOI: 10.1016/j.adro.2020.06.006
Abstract: Purpose Lung reirradiation for nonsmall cell lung cancer (NSCLC) is common for either recurrent disease or new primary cancer. Dose volume tolerance of the lung after multiple courses of radiation therapy (RT) is unknown. We… read more here.
Keywords: radiation therapy; lung; nonsmall cell; cancer ... See more keywords
Antimicrobial peptides as novel therapeutics for nonsmall cell lung cancer.
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DOI: 10.1016/j.drudis.2019.11.012
Abstract: Lung cancer is the second most common cancer in both men and women. Of all the lung cancer cases reported, 85% are nonsmall cell lung cancer (NSCLC). Although current treatments have improved the overall survival… read more here.
Keywords: cell lung; nonsmall cell; antimicrobial peptides; lung cancer ... See more keywords
Advancing Nonsmall Cell Lung Cancer Diagnosis Accuracy via Dual Detection Fluorescent Nanoprobes.
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DOI: 10.1021/acs.analchem.4c00794
Abstract: Among the primary threats to human health worldwide, nonsmall cell lung cancer (NSCLC) remains a significant factor and is a leading cause of cancer-related deaths. Due to subtle early symptoms, NSCLC patients are diagnosed at… read more here.
Keywords: detection; cancer; lung; lung cancer ... See more keywords
Developing a Copper(II) Agent Based on His-146 and His-242 Residues of Human Serum Albumin Nanoparticles: Integration To Overcome Cisplatin Resistance and Inhibit the Metastasis of Nonsmall Cell Lung Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c00698
Abstract: To overcome the resistance of nonsmall cell lung cancer (NSCLC) cells to cisplatin and inhibit their metastasis, we proposed to develop a Cu(II) agent based on the specific residue(s) of HSA nanoparticles (NPs) for multitargeting… read more here.
Keywords: metastasis; lung cancer; hsa; resistance ... See more keywords
Preparation of Biomimetic Selenium-Baicalein Nanoparticles and Their Targeted Therapeutic Application in Nonsmall Cell Lung Cancer.
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DOI: 10.1021/acs.molpharmaceut.4c00390
Abstract: In this study, we prepared bionic selenium-baicalein nanoparticles (ACM-SSe-BE) for the targeted treatment of nonsmall cell lung cancer. Due to the coating of the A549 membrane, the system has homologous targeting capabilities, allowing for the… read more here.
Keywords: acm sse; selenium; lung cancer; nonsmall cell ... See more keywords
Bioorthogonal Chemistry-Guided Inhalable Nanoprodrug to Circumvent Cisplatin Resistance in Orthotopic Nonsmall Cell Lung Cancer.
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DOI: 10.1021/acsnano.4c10947
Abstract: Pulmonary delivery of anticancer therapeutics has shown encouraging performance in treating nonsmall cell lung cancer (NSCLC), which is characterized by high aggressiveness and poor prognosis. Cisplatin, a key member of the family of DNA alkylating… read more here.
Keywords: chemistry; cisplatin; lung cancer; nonsmall cell ... See more keywords
Digoxin exerts anticancer activity on human nonsmall cell lung cancer cells by blocking PI3K/Akt pathway
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DOI: 10.1042/bsr20211056
Abstract: Abstract Lung cancer remains the leading cause of cancer mortality because of its metastatic potential and high malignancy. The discovery of new applications for old drugs is a shortcut for cancer therapy. We recently investigated… read more here.
Keywords: cell; digoxin; nonsmall cell; lung cancer ... See more keywords