Elevated air quality index and fine particulate matter levels contribute to the poor prognosis and progression of nonsmall‐cell lung cancer: A cohort study combined with external validation
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DOI: 10.1002/cam4.4701
Abstract: Poor air quality can result in a variety of respiratory disorders. However, the air quality index (AQI) and the level of fine particulate matter (PM2.5) on the progression and prognosis of nonsmall‐cell lung cancer (NSCLC)… read more here.
Keywords: quality index; fine particulate; particulate matter; nonsmall cell ... See more keywords
Repeat Thoracic Stereotactic Body Radiation Therapy (SBRT) for Nonsmall Cell Lung Cancer: Long-Term Outcomes, Toxicity, and Dosimetric Considerations
Sign Up to like & getrecommendations! Published in 2020 at "Advances in Radiation Oncology"
DOI: 10.1016/j.adro.2020.06.006
Abstract: Purpose Lung reirradiation for nonsmall cell lung cancer (NSCLC) is common for either recurrent disease or new primary cancer. Dose volume tolerance of the lung after multiple courses of radiation therapy (RT) is unknown. We… read more here.
Keywords: radiation therapy; lung; nonsmall cell; cancer ... See more keywords
Antimicrobial peptides as novel therapeutics for nonsmall cell lung cancer.
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DOI: 10.1016/j.drudis.2019.11.012
Abstract: Lung cancer is the second most common cancer in both men and women. Of all the lung cancer cases reported, 85% are nonsmall cell lung cancer (NSCLC). Although current treatments have improved the overall survival… read more here.
Keywords: cell lung; nonsmall cell; antimicrobial peptides; lung cancer ... See more keywords
Developing a Copper(II) Agent Based on His-146 and His-242 Residues of Human Serum Albumin Nanoparticles: Integration To Overcome Cisplatin Resistance and Inhibit the Metastasis of Nonsmall Cell Lung Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c00698
Abstract: To overcome the resistance of nonsmall cell lung cancer (NSCLC) cells to cisplatin and inhibit their metastasis, we proposed to develop a Cu(II) agent based on the specific residue(s) of HSA nanoparticles (NPs) for multitargeting… read more here.
Keywords: metastasis; lung cancer; hsa; resistance ... See more keywords
Digoxin exerts anticancer activity on human nonsmall cell lung cancer cells by blocking PI3K/Akt pathway
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DOI: 10.1042/bsr20211056
Abstract: Abstract Lung cancer remains the leading cause of cancer mortality because of its metastatic potential and high malignancy. The discovery of new applications for old drugs is a shortcut for cancer therapy. We recently investigated… read more here.
Keywords: cell; digoxin; nonsmall cell; lung cancer ... See more keywords
Targeted drug therapy in nonsmall cell lung cancer: clinical significance and possible solutions-part II (role of nanocarriers)
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DOI: 10.1080/17425247.2021.1832989
Abstract: ABSTRACT Introduction Nonsmall cell lung cancer (NSCLC) accounts for 80–85% of the cases of lung cancer. The conventional therapeutic effective dosage forms used to treat NSCLC are associated with rigid administration schedules, adverse effects, and… read more here.
Keywords: drug; nonsmall cell; delivery; lung cancer ... See more keywords
Opioid Dose and Survival of Patients with Incurable Nonsmall Cell Lung Cancer: A Prospective Cohort Study.
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DOI: 10.1089/jpm.2018.0044
Abstract: BACKGROUND Preclinical studies show that opioids promote angiogenesis, tumor progression, and metastasis, resulting in shorter survival. OBJECTIVE To explore whether opioids are associated with the overall survival (OS) of patients with incurable nonsmall cell lung… read more here.
Keywords: incurable nonsmall; cell lung; survival patients; nonsmall cell ... See more keywords
Intracranial Response of Brain Metastases to Osimertinib With or Without Upfront Stereotactic Radiosurgery in TKI-Naïve Nonsmall Cell Lung Cancer Patients
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DOI: 10.1093/neuros/nyz310_643
Abstract: Stereotactic radiosurgery (SRS) is an accepted standard of care for the treatment of brain metastases. However, the benefit of upfront SRS in combination with osimertinib, which has excellent intracranial penetrance, for patients with EGFR-mutant nonsmall… read more here.
Keywords: response; stereotactic radiosurgery; nonsmall cell; cell lung ... See more keywords
Hyperprogression after first dose of immunotherapy in a patient with radioresistant metastasis from nonsmall cell lung cancer.
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DOI: 10.1097/cad.0000000000000837
Abstract: Immune checkpoint inhibitors (ICIs) represent a new standard of care for patients with advanced nonsmall cell lung cancer, improving overall survival compared with standard chemotherapy. However, a new pattern of response to ICIs characterized by… read more here.
Keywords: lung; lung cancer; cancer; nonsmall cell ... See more keywords
CD47-SIRPα Axis as a Biomarker and Therapeutic Target in Cancer: Current Perspectives and Future Challenges in Nonsmall Cell Lung Cancer
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DOI: 10.1155/2020/9435030
Abstract: CD47 is a cell surface protein in the immunoglobulin superfamily which is normally expressed at low levels in every healthy cell. It´s main physiologic function is to act as an inhibitor of phagocytosis; this occurs… read more here.
Keywords: biomarker therapeutic; cd47; nonsmall cell; target cancer ... See more keywords
Baicalin Inhibits EMT through PDK1/AKT Signaling in Human Nonsmall Cell Lung Cancer
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DOI: 10.1155/2021/4391581
Abstract: Background Baicalin is a naturally occurring compound with anticancer, antioxidant, and anti-inflammatory properties. However, the mechanism underlying its anticancer activity on nonsmall cell lung cancer (NSCLC) remains unclear. Methods The effects of baicalin on the… read more here.
Keywords: cell lung; pdk1 akt; cell; lung cancer ... See more keywords