Articles with "nonsteroidal farnesoid" as a keyword



Evaluation of the Effects of Meal Type and Acid‐Reducing Agents on the Pharmacokinetics of Cilofexor, a Selective Nonsteroidal Farnesoid X Receptor Agonist

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Published in 2024 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.1384

Abstract: Cilofexor is a nonsteroidal farnesoid X receptor agonist being developed in combination with firsocostat/semaglutide for the treatment of nonalcoholic steatohepatitis. This phase 1 study evaluated the effects of food and acid‐reducing agents (ARAs) on the… read more here.

Keywords: nonsteroidal farnesoid; fasting conditions; evaluated effects; receptor agonist ... See more keywords