A pan-cancer analysis reveals nonstop extension mutations causing SMAD4 tumour suppressor degradation
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DOI: 10.1038/s41556-020-0551-7
Abstract: Nonstop or stop-loss mutations convert a stop into a sense codon, resulting in translation into the 3′ untranslated region as a nonstop extension mutation to the next in-frame stop codon or as a readthrough mutation… read more here.
Keywords: cancer; nonstop extension; extension; tumour suppressor ... See more keywords