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Published in 2017 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.6b04604
Abstract: Metabolic bioactivation of many different chemicals results in the formation of highly reactive compounds (chemically reactive metabolites, CRMs) that can lead to toxicity via binding to macromolecular targets (e.g., proteins or DNA). There is a…
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Keywords:
protein;
reactive metabolite;
nontargeted identification;
identification reactive ... See more keywords