Efflux pump inhibitor combined with ofloxacin decreases MRSA biofilm formation by regulating the gene expression of NorA and quorum sensing
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DOI: 10.1039/d2ra06696c
Abstract: Carbonyl cyanide p-nitrophenylhydrazone (2e) displayed a lone or synergistic efficacy against MRSA (RSC Adv., 2020, 10, 17854). In this work, the synergistic mechanism of 2e with ofloxacin was studied. MRSA2858 had potential for biofilm formation,… read more here.
Keywords: biofilm formation; nora quorum; efflux pump; combined ofloxacin ... See more keywords