Self-Forming Norbornene-Tetrazine Hydrogels with Independently Tunable Properties.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200425
Abstract: Although photopolymerization reactions are commonly used to form hydrogels, these strategies rely on light and may not be suitable for delivering therapeutics in a minimally invasive manner. Here, hyaluronic acid (HA) macromers are modified with… read more here.
Keywords: norbornene tetrazine; tet hydrogels; self forming; tet ... See more keywords
Norbornene-tetrazine ligation chemistry for controlling RNA-guided CRISPR systems
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc02635j
Abstract: In the present study, norbornene-tetrazine ligation chemistry is harnessed for developing clickable RNA switches in biological contexts. This RNA control strategy is explored with a variety of applications. We further demonstrate the application of RNA-based… read more here.
Keywords: norbornene tetrazine; chemistry; rna; tetrazine ligation ... See more keywords