Synthesis and Cytotoxicity of Octahydroepoxyisoindole‐7‐carboxylic Acids and Norcantharidin–Amide Hybrids as Norcantharidin Analogues
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DOI: 10.1002/cmdc.201900180
Abstract: Octahydroepoxyisoindole analogues of norcantharidin were accessed through a Diels–Alder reaction of an amine‐substituted furan with maleic anhydride and subsequent reduction of the bicyclo[2.2.1]heptene olefin. Despite retention of the carboxylate and the ether bridgehead known to… read more here.
Keywords: norcantharidin analogues; synthesis cytotoxicity; carboxylic acids; cytotoxicity octahydroepoxyisoindole ... See more keywords