Structural Evidence for the Dopamine-First Mechanism of Norcoclaurine Synthase
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DOI: 10.1021/acs.biochem.7b00769
Abstract: Norcoclaurine synthase (NCS) is a Pictet-Spenglerase that catalyzes the first key step in plant benzylisoquinoline alkaloid metabolism, a compound family that includes bioactive natural products such as morphine. The enzyme has also shown great potential… read more here.
Keywords: norcoclaurine synthase; mechanism; dopamine first; structural evidence ... See more keywords