Lipoxygenase Inhibitors Nordihydroguaiaretic Acid and Fungus Lecanicillum lecanii Extract Induce Death of Lymphoid Leukemia Cells
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DOI: 10.1007/s10517-017-3796-9
Abstract: We studied the effect of lipoxygenase inhibitors nordihydroguaiaretic acid (NDGA) and fungus Lecanicillum lecanii extract on lymphatic leukemia P388 cells. The cells grown in the abdominal cavity of DBA2 mice for 7 days were transferred… read more here.
Keywords: fungus; inhibitors nordihydroguaiaretic; nordihydroguaiaretic acid; fungus lecanicillum ... See more keywords
First report of antiviral activity of nordihydroguaiaretic acid against Fort Sherman virus (Orthobunyavirus).
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DOI: 10.1016/j.antiviral.2020.104976
Abstract: The genus Orthobunyavirus are a group of viruses within arbovirus, with a zoonotic cycle, some of which could lead to human infection. A characteristic of these viruses is their lack of antiviral treatment or vaccine… read more here.
Keywords: activity nordihydroguaiaretic; antiviral activity; nordihydroguaiaretic acid; activity ... See more keywords
NDGA-P21, a novel derivative of nordihydroguaiaretic acid, inhibits glioma cell proliferation and stemness
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DOI: 10.1038/labinvest.2017.46
Abstract: Nordihydroguaiaretic acid (NDGA) and its synthetic chiral analog dl-nordihydroguaiaretic acid (Nordy) show collective benefits in anti-tumor, and defending against viral and bacterial infections. Here, we synthetized a new derivative-NDGA-P21 based on NDGA structure. Regardless of… read more here.
Keywords: cell; ndga p21; nordihydroguaiaretic acid; p21 ... See more keywords
Antitumor Effects of Nordihydroguaiaretic Acid (NDGA) in Bladder T24 Cancer Cells are Related to Increase in ROS Production and Mitochondrial Leak Respiration
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DOI: 10.1177/1934578x1801301128
Abstract: The aim of this study was to evaluate the effect of nordihydroguaiaretic acid (NDGA) on tumor bladder T24 cells. Bladder cancer T24 cells were cultured on Dulbecco's Modified Eagle Medium in presence of NDGA. Cell… read more here.
Keywords: bladder t24; nordihydroguaiaretic acid; bladder; respiration ... See more keywords