The role of the NORE1A tumor suppressor in Oncogene-Induced Senescence.
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DOI: 10.1016/j.canlet.2017.04.030
Abstract: The Ras genes are the most frequently mutated oncogenes in human cancer. However, Ras biology is quite complex. While Ras promotes tumorigenesis by regulating numerous growth promoting pathways, activated Ras can paradoxically also lead to… read more here.
Keywords: oncogene induced; role nore1a; nore1a tumor; induced senescence ... See more keywords