Echocardiographic measure of dynamic arterial elastance predict pressure response during norepinephrine weaning: an observational study
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-82408-9
Abstract: The purpose of this study was to determine whether dynamic elastance EAdyn derived from echocardiographic measurements of stroke volume variations can predict the success of a one-step decrease of norepinephrine dose. In this prospective single-center… read more here.
Keywords: variation; stroke volume; study; norepinephrine ... See more keywords
A Prospective double-blind, randomised controlled trial comparing angiotensin II to norepinephrine to reduce length of hospital stay in cardiac surgery patients (the PORTHOS study protocol)
Sign Up to like & getrecommendations! Published in 2025 at "BMJ Open"
DOI: 10.1136/bmjopen-2024-095099
Abstract: Introduction Cardiac surgery is frequently associated with vasoplegia and vasopressor treatment. Both may be associated with postoperative complications and prolonged length of stay. The most frequently used vasopressor is norepinephrine. However, in a pilot, double-blind,… read more here.
Keywords: double blind; surgery; norepinephrine; stay ... See more keywords
Fast in vivo detection of myocardial norepinephrine levels in the beating porcine heart
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Physiology - Heart and Circulatory Physiology"
DOI: 10.1152/ajpheart.00574.2019
Abstract: The sympathetic nervous system modulates cardiac function by controlling key parameters such as chronotropy and inotropy. Sympathetic control of ventricular function occurs through extrinsic innervation arising from the stellate ganglia and thoracic sympathetic chain. In… read more here.
Keywords: porcine heart; heart; beating porcine; levels beating ... See more keywords
Effect Evaluation of Norepinephrine on Cardiac Function in Patients with Sepsis by Cardiac Ultrasound Imaging
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/5896791
Abstract: In order to investigate the therapeutic effect of norepinephrine on patients with sepsis and the effect of echocardiography on the diagnosis of cardiac function in patients with sepsis, 86 patients with sepsis were selected as… read more here.
Keywords: function patients; effect; cardiac function; norepinephrine ... See more keywords
Timing of Vasopressin Addition to Norepinephrine and Efficacy Outcomes in Patients With Septic Shock
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Pharmacotherapy"
DOI: 10.1177/10600280221118903
Abstract: Background: Current guidelines recommend norepinephrine as the first-line vasopressor in septic shock followed by addition of vasopressin to achieve a goal mean arterial pressure. Limited evidence exists evaluating how the timing of vasopressin addition affects… read more here.
Keywords: addition; norepinephrine; septic shock; vasopressin addition ... See more keywords
Comment on “Vasoplegic syndrome following cardiothoracic surgery-review of pathophysiology and update of treatment options”
Sign Up to like & getrecommendations! Published in 2020 at "Critical Care"
DOI: 10.1186/s13054-020-02854-1
Abstract: We read with great interest the article by Bousse et al. on vasoplegic syndrome after cardiothoracic surgery [1]. It provides an excellent review of alternative pharmacologic interventions when vasodilatory shock becomes refractory to usual measures… read more here.
Keywords: article; vasoplegic syndrome; min norepinephrine; norepinephrine ... See more keywords
Norepinephrine potentiates the efficacy of volume expansion on mean systemic pressure in septic shock
Sign Up to like & getrecommendations! Published in 2021 at "Critical Care"
DOI: 10.1186/s13054-021-03711-5
Abstract: Through venous contraction, norepinephrine (NE) increases stressed blood volume and mean systemic pressure (Pms) and exerts a “fluid-like” effect. When both fluid and NE are administered, Pms may not only result from the sum of… read more here.
Keywords: pms; volume; septic shock; norepinephrine ... See more keywords
Dynamic arterial elastance as a predictor of arterial pressure response to norepinephrine weaning in mechanically ventilated patients with vasoplegic syndrome—a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2024.1350847
Abstract: Introduction During the de-escalation phase of circulatory shock, norepinephrine weaning may induce diverse arterial pressure responses in patients with different vasomotor tones. Dynamic arterial elastance (Eadyn) has been extensively studied to predict the arterial pressure… read more here.
Keywords: norepinephrine; norepinephrine weaning; response norepinephrine; patients vasoplegic ... See more keywords
A Focus on the Link Between Metal Dyshomeostasis, Norepinephrine, and Protein Aggregation
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DOI: 10.3390/antiox14030347
Abstract: Neurodegenerative disorders are one of the main public health problems worldwide and, for this reason, they have attracted the attention of several researchers who aim to better understand the molecular processes linked to the etiology… read more here.
Keywords: norepinephrine; focus link; protein; protein aggregation ... See more keywords
The Dual Role of the β2-Adrenoreceptor in the Modulation of IL-17 and IFN-γ Production by T Cells in Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020668
Abstract: Norepinephrine is a neurotransmitter that also has an immunomodulatory effect and is involved in multiple sclerosis (MS) pathogenesis. This study aimed to clarify the role of the β2-adrenoreceptor in the norepinephrine-mediated modulation of interleukin-17 (IL-17)… read more here.
Keywords: ifn production; norepinephrine; adrenoreceptor; production ... See more keywords