Sustained chemogenetic activation of locus coeruleus norepinephrine neurons promotes dopaminergic neuron survival in synucleinopathy
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DOI: 10.1371/journal.pone.0263074
Abstract: Dopaminergic neuron degeneration in the midbrain plays a pivotal role in motor symptoms associated with Parkinson’s disease. However, non-motor symptoms of Parkinson’s disease and post-mortem histopathology confirm dysfunction in other brain areas, including the locus… read more here.
Keywords: dopaminergic neuron; norepinephrine neurons; locus coeruleus;