Survey of the Arc Epigenetic Landscape in Normal Cognitive Aging
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Neurobiology"
DOI: 10.1007/s12035-020-01915-4
Abstract: Aging is accompanied by aberrant gene expression that ultimately affects brain plasticity and the capacity to form long-term memories. Immediate-early genes (IEGs) play an active role in these processes. Using a rat model of normal… read more here.
Keywords: epigenetic landscape; cognitive aging; expression; arc epigenetic ... See more keywords
How does decisional capacity evolve with normal cognitive aging: systematic review of the literature
Sign Up to like & getrecommendations! Published in 2019 at "European Geriatric Medicine"
DOI: 10.1007/s41999-019-00251-8
Abstract: Aim The complexity of decision-making involves many neurological functions and structures which are potentially altered by cognitive aging. Findings Our systematic review shows a decrease in processing speed in normal aging, usually compensated by experience.… read more here.
Keywords: decision; systematic review; cognitive aging; decision making ... See more keywords
Normal cognitive and social development require posterior cerebellar activity
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DOI: 10.7554/elife.36401
Abstract: Cognitive and social capacities require postnatal experience, yet the pathways by which experience guides development are unknown. Here we show that the normal development of motor and nonmotor capacities requires cerebellar activity. Using chemogenetic perturbation… read more here.
Keywords: cognitive social; social development; normal cognitive; activity ... See more keywords