The impact on estimations of genetic correlations by the use of super‐normal, unscreened, and family‐history screened controls in genome wide case–control studies
Sign Up to like & getrecommendations! Published in 2020 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22281
Abstract: Traditionally, in normal case–control studies of disorder A, the controls are defined as those not developing the disorder. However, in genome wide association (GWA) studies, controls are sometimes (a) unscreened or (b) screened for both… read more here.
Keywords: genome wide; control studies; genetic correlations; normal controls ... See more keywords
Metabolic profiling of acromegaly using a GC–MS-based nontargeted metabolomic approach
Sign Up to like & getrecommendations! Published in 2019 at "Endocrine"
DOI: 10.1007/s12020-019-02143-0
Abstract: Purpose Acromegaly is a rare disease caused by chronic hypersecretion of growth hormone, which leads to multiple comorbidities and reduced life expectancy. The objective of this study was to characterize the serum metabolic profiles of… read more here.
Keywords: acromegaly; glyceric acid; normal controls; acid ... See more keywords
Detection of hemophilia by fluorescence spectroscopy: A photodiagnosis approach.
Sign Up to like & getrecommendations! Published in 2019 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2019.101598
Abstract: Hemophilia (HP), the deficiency of clotting factors such as VIII (FVIII) and IX, is an inherited blood disorder which is due to the lack of clotting protein. Conventional techniques for detecting hemophilia are based on… read more here.
Keywords: detection; detection hemophilia; hemophilia patients; spectroscopy ... See more keywords
Corneal Biomechanics in Primary Open Angle Glaucoma and Ocular Hypertension: A Systematic Review and Meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Glaucoma"
DOI: 10.1097/ijg.0000000000002170
Abstract: Précis: Normal tension glaucoma patients had softer corneas than normal controls, whereas high-tension glaucoma and ocular hypertension patients had stiffer corneas. Purpose: To comprehensively identify the corneal biomechanical differences of patients with primary open angle… read more here.
Keywords: glaucoma; oht patients; normal controls; ocular hypertension ... See more keywords
Corrugator: Muscle of Empathy and Determination.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Craniofacial Surgery"
DOI: 10.1097/scs.0000000000003013
Abstract: FIGURE 1. Sir Winston Churchill (1874–1965). A ccording to Gray’ ator supercilii muscle arises from the medial end of the superciliary arch and inserts into the deep surface of the skin, above the middle of… read more here.
Keywords: corrugator muscle; corrugator; muscle; muscle empathy ... See more keywords
Magnetic Resonance Imaging Texture of Medial Pulvinar in Dementia with Lewy Bodies
Sign Up to like & getrecommendations! Published in 2020 at "Dementia and Geriatric Cognitive Disorders"
DOI: 10.1159/000506798
Abstract: Introduction: Executive dysfunction is common in dementia with Lewy bodies (DLB). The pulvinar nucleus plays a role in executive control and synchronizes with cortical regions in the salience network that are vulnerable to Lewy pathology.… read more here.
Keywords: dementia lewy; pulvinar; dlb patients; normal controls ... See more keywords
Investigating the Role of the Gut Microbiome in the Inflammatory State of Myeloproliferative Neoplasms
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-109761
Abstract: The human microbiome is composed of trillions of micro-organisms living in symbiosis with the human body. The interest in the microbiome and the clinical impact of its disruption (dysbiosis) has grown exponentially in the past… read more here.
Keywords: mpn; symptom burden; inflammatory; mpn patients ... See more keywords
Comparison of atherosclerotic inflammation and calcification in subjects with end stage renal disease (ESRD) on hemodialysis to normal controls utilizing 18F-FDG PET/CT.
Sign Up to like & getrecommendations! Published in 2018 at "Hellenic journal of nuclear medicine"
DOI: 10.1967/s002449910901
Abstract: OBJECTIVE Subjects with end stage renal disease (ESRD) are exposed to increased morbidity and mortality due to cardiovascular events. The primary underlying mechanism has been suggested as accelerated atherosclerosis in these patients. Our aim was… read more here.
Keywords: calcification; fdg pet; subjects esrd; normal controls ... See more keywords
Quantitative and qualitative analysis of fetal temporal lobe T2 signal in cytomegalovirus infected fetuses and normal controls.
Sign Up to like & getrecommendations! Published in 2021 at "Quantitative imaging in medicine and surgery"
DOI: 10.21037/qims-21-22
Abstract: Background Temporal lobe T2 hyperintensity has been described in association with prenatal cytomegalovirus (CMV) infection on fetal MRI. However, these findings are often perplexing with high inter-observer variability. Our objective was to evaluate temporal lobe… read more here.
Keywords: temporal lobe; infected fetuses; normal controls; lobe signal ... See more keywords
Neurohormonal markers in chronic rhinosinusitis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biological regulators and homeostatic agents"
DOI: 10.23812/21-35-3-e2
Abstract: Chronic rhinosinusitis (CRS), especially with nasal polyps, continues to elude precise pathogenesis and effective treatment. Prior work in our laboratory demonstrated interleukin-33 (IL-33) and Substance P (SP) activation of mast cells, and inhibitory effect of… read more here.
Keywords: lavage fluid; gene expression; tissue; normal controls ... See more keywords
Biomechanical Evaluation of Topographically and Tomographically Normal Fellow Eyes of Patients With Keratoconus.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of refractive surgery"
DOI: 10.3928/1081597x-20220225-01
Abstract: PURPOSE To determine the effectiveness of parameters and indices based on biomechanical measures at discriminating fellow eyes with topographically and tomographically normal corneas in patients with keratoconus from normal control corneas. METHODS The study included… read more here.
Keywords: topographically tomographically; patients keratoconus; fellow eyes; tomographically normal ... See more keywords