Effects of Human Mesenchymal Stem Cells Coculture on Calcium‐Induced Differentiation of Normal Human Keratinocytes
Sign Up to like & getrecommendations! Published in 2017 at "STEM CELLS"
DOI: 10.1002/stem.2593
Abstract: The influence of mesenchymal stem cells (MSCs) on keratinocytes in altered microenvironments is poorly understood. Here, we cocultured umbilical cord blood‐derived MSCs with normal human epidermal keratinocytes to evaluate their paracrine effect in the presence… read more here.
Keywords: differentiation; normal human; ca2; stem cells ... See more keywords
Tibolone Ameliorates the Lipotoxic Effect of Palmitic Acid in Normal Human Astrocytes
Sign Up to like & getrecommendations! Published in 2020 at "Neurotoxicity Research"
DOI: 10.1007/s12640-020-00247-4
Abstract: Lipotoxicity is a pathological condition resulting from the excessive accumulation of fatty acids, like palmitic acid (PA), within the cell. This pathological phenomenon induces deleterious metabolic changes in cells and is associated with neurodegenerative diseases,… read more here.
Keywords: palmitic acid; ameliorates lipotoxic; tibolone ameliorates; human astrocytes ... See more keywords
Chlortetracycline and melanin biopolymer - The risk of accumulation and implications for phototoxicity: An in vitro study on normal human melanocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2019.02.005
Abstract: Tetracyclines belong to antimicrobial classes with the highest consumption in veterinary medicine and agriculture, which leads to the contamination of the environment and food products, as well as to antibiotic resistance and adverse drug reactions.… read more here.
Keywords: accumulation; melanin; study; drug ... See more keywords
Transcriptome analysis in normal human liver cells exposed to 2, 3, 3', 4, 4', 5 - Hexachlorobiphenyl (PCB 156).
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.124747
Abstract: BACKGROUNDS Polychlorinated biphenyls are persistent environmental pollutants associated with the onset of non-alcoholic fatty liver disease in humans, but there is limited information on the underlying mechanism. In the present study, we investigated the alterations… read more here.
Keywords: analysis; cells exposed; liver; normal human ... See more keywords
Synthesis and characterization of polyglycerol coated superparamagnetic iron oxide nanoparticles and cytotoxicity evaluation on normal human cell lines
Sign Up to like & getrecommendations! Published in 2018 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2018.05.003
Abstract: Abstract Superparamagnetic iron oxide nanoparticles (SPIONs) are considered as interesting nano-carriers for cancer detection and treatment. As promising reagents for biomedical applications they need surface modifications and polyglycerol has shown suitable characteristics as a coating… read more here.
Keywords: iron oxide; cell lines; oxide nanoparticles; normal human ... See more keywords
In vitro dosimetry analyses for acrolein exposure in normal human lung epithelial cells and human lung cancer cells.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2020.103576
Abstract: Establishing accurate dosimetry is important for assessing the toxicity of xenobiotics as well as for comparing responses between different test systems. In this study, we used acrolein as a model toxicant and defined the concentration-response… read more here.
Keywords: acrolein exposure; gsh; human lung; normal human ... See more keywords
Phenomenology and outcomes of acute antioxidative stress in normal human cells
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.417
Abstract: A number of clinical trials have shown harmful effects of high-dosage antioxidant (AO) interventions. Antioxidative stress defined as a negative impact of pharmacological AOs on cells and tissues is one of the concepts being discussed… read more here.
Keywords: antioxidative stress; stress; normal human; phenomenology outcomes ... See more keywords
Wnt5a induces catabolic signaling and matrix metalloproteinase production in human articular chondrocytes.
Sign Up to like & getrecommendations! Published in 2017 at "Osteoarthritis and cartilage"
DOI: 10.1016/j.joca.2017.05.018
Abstract: OBJECTIVE Aberrant Wnt signaling may contribute to osteoarthritis (OA) but the Wnt family members involved have not been fully identified. The purpose of this study was to investigate the role of Wnt5a as a potential… read more here.
Keywords: production; kinase; normal human; wnt5a ... See more keywords
Generation of nonviral integration-free human iPS cell line KISCOi001-A from normal human fibroblasts, under defined xeno-free and feeder-free conditions.
Sign Up to like & getrecommendations! Published in 2021 at "Stem cell research"
DOI: 10.1016/j.scr.2021.102193
Abstract: KISCOi001-A is a healthy feeder-free and fully characterized human induced pluripotent stem (iPS) cell line cultured under xeno-free and defined conditions. The cell line is generated from normal human foreskin fibroblasts with non-integrating episomal plasmid… read more here.
Keywords: cell line; line; feeder free; ips cell ... See more keywords
Identification of Missing Proteins in Normal Human Cerebrospinal Fluid.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.8b00194
Abstract: The cerebrospinal fluid (CSF) proteome data set presented herein was obtained after immunodepletion of abundant proteins and off-gel electrophoresis fractionation of a commercial pool of normal human CSF; liquid chromatography tandem mass spectrometry analysis was… read more here.
Keywords: missing proteins; normal human; identification; data set ... See more keywords
Morphological and Molecular Changes in Juvenile Normal Human Fibroblasts Exposed to Simulated Microgravity
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-48378-9
Abstract: The literature suggests morphological alterations and molecular biological changes within the cellular milieu of human cells, exposed to microgravity (µg), as many cell types assemble to multicellular spheroids (MCS). In this study we investigated juvenile… read more here.
Keywords: molecular changes; changes juvenile; normal human; morphological molecular ... See more keywords