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   Articles with "normal lung" as a keyword



13PCharacterizing the DNA damage response in putative stem cells of resected normal lung and matched NSCLC patient samples

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recommendations! Published in 2017 at "Annals of Oncology"

DOI: 10.1093/annonc/mdx090.013

Abstract: Background More than 80% of lung tumors are non-small cell lung cancers (NSCLC). Tumor initiation and propagation are mediated by tumor initiating cells (TICs). In NSCLC and glioblastoma, TICs are characterized by high glycine decarboxylase… read more here.

Keywords: epcam gldc; dna damage; normal lung; lung ... See more keywords

Abstract 6524: Single-cell transcriptomic analysis reveals immune landscape in the malignant transformation of normal lung to lung adenocarcinoma in genetic murine models

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recommendations! Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-6524

Abstract: Background: Our understanding of the initiation and progression of lung precancers is rudimentary, which has impeded advance for lung cancer prevention and interception. Although human specimens are the gold standard to study human cancer biology,… read more here.

Keywords: normal lung; lung adenocarcinoma; lung; single cell ... See more keywords

Comorbidity between lung cancer and COVID-19 pneumonia: role of immunoregulatory gene transcripts in high ACE2-expressing normal lung

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recommendations! Published in 2022 at "Therapeutic Advances in Medical Oncology"

DOI: 10.1177/17588359221133893

Abstract: Background: SARS-CoV-2 (COVID-19) elicits a T-cell antigen-mediated immune response of variable efficacy. To understand this variability, we explored transcriptomic expression of angiotensin-converting enzyme 2 (ACE2, the SARS-CoV-2 receptor) and of immunoregulatory genes in normal lung… read more here.

Keywords: normal lung; high ace2; expression; lung ... See more keywords

Expiratory reactance abnormalities in patients with expiratory dynamic airway collapse: a new application of impulse oscillometry

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recommendations! Published in 2018 at "ERJ Open Research"

DOI: 10.1183/23120541.00080-2018

Abstract: Expiratory dynamic airways collapse (EDAC) is a condition that affects the central airways; it is not well characterised physiologically, with relatively few studies. We sought to characterise impulse oscillometry (IOS) features of EDAC in patients… read more here.

Keywords: normal lung; collapse; reactance; expiratory dynamic ... See more keywords

Cellular transcriptomics of arrested normal lung fibroblasts IMR-90 infected with Human Adenovirus 5 E1A mutants

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recommendations! Published in 2025 at "PLOS One"

DOI: 10.1371/journal.pone.0323494

Abstract: Induction of S-phase is paramount to the replication of most human DNA viruses. Human adenoviruses have evolved sophisticated mechanisms that drive the infected cells into S-phase to ensure that viral genomes are efficiently replicated. We… read more here.

Keywords: transcriptomics arrested; arrested normal; normal lung; cellular transcriptomics ... See more keywords

A Volumetric Computed Tomography Analysis of the Normal Lung in Idiopathic Pulmonary Fibrosis: The Relationship with the Survival

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recommendations! Published in 2018 at "Internal Medicine"

DOI: 10.2169/internalmedicine.9508-17

Abstract: Objective An image analysis of high-resolution computed tomography (HRCT) can provide objective quantitation of the disease status in idiopathic pulmonary fibrosis (IPF). However, to our knowledge, no reports have investigated the utility of the normal… read more here.

Keywords: computed tomography; normal lung; idiopathic pulmonary; analysis ... See more keywords

Forkhead box N1 is possibly a novel biomarker and prognostic indicator for patients with squamous cell lung carcinoma

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recommendations! Published in 2024 at "International Journal of Medical Sciences"

DOI: 10.7150/ijms.104616

Abstract: Background: The roles of Forkhead box N1 (FOXN1) in lung squamous cell carcinoma (LUSC) remains elusive. This study was focused on assessing the expression levels of FOXN1 in LUSC and exploring its potential clinical implications.… read more here.

Keywords: lung; forkhead box; lusc; normal lung ... See more keywords