Tracking B-Cell Repertoires and Clonal Histories in Normal and Malignant Lymphocytes.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7095-7_21
Abstract: Methods for tracking B-cell repertoires and clonal history in normal and malignant B-cells based on immunoglobulin variable region (IGV) gene analysis have developed rapidly with the advent of massive parallel next-generation sequencing (mpNGS) protocols. mpNGS… read more here.
Keywords: normal malignant; cell repertoires; analysis; repertoires clonal ... See more keywords
Matrix Gla protein maintains normal and malignant hematopoietic progenitor cells by interacting with bone morphogenetic protein-4
Sign Up to like & getrecommendations! Published in 2020 at "Heliyon"
DOI: 10.1016/j.heliyon.2020.e03743
Abstract: Matrix Gla protein (MGP), a modulator of the BMP-SMAD signals, inhibits arterial calcification in a Glu γ-carboxylation dependent manner but the role of MGP highly expressed in a subset of bone marrow (BM) mesenchymal stem/stromal… read more here.
Keywords: protein; bmp; normal malignant; stromal cells ... See more keywords
TET2 in Normal and Malignant Hematopoiesis.
Sign Up to like & getrecommendations! Published in 2017 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a026518
Abstract: The ten-eleven translocation (TET) family of enzymes were originally cloned from the translocation breakpoint of t(10;11) in infant acute myeloid leukemia (AML) with subsequent genomic analyses revealing somatic mutations and suppressed expression of TET family… read more here.
Keywords: hematopoiesis; tet family; tet2 normal; normal malignant ... See more keywords
Ultra-Wideband Millimeter-Wave Dielectric Characteristics of Freshly Excised Normal and Malignant Human Skin Tissues
Sign Up to like & getrecommendations! Published in 2018 at "IEEE Transactions on Biomedical Engineering"
DOI: 10.1109/tbme.2017.2749371
Abstract: Millimeter waves have recently gained attention for the evaluation of skin lesions and the detection of skin tumors. Such evaluations heavily rely on the dielectric contrasts existing between normal and malignant skin tissues at millimeter-wave… read more here.
Keywords: normal malignant; skin; millimeter wave; ultra wideband ... See more keywords
Abstract IA008: Charting normal and malignant differentiation topologies with single-cell multi-omics
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Research"
DOI: 10.1158/1538-7445.evodyn22-ia008
Abstract: Somatic evolution is a novel emerging frontier in human biology, as cells within diverse normal and malignant tissues have been shown to diversify and undergo selection. We and others have shown that somatic evolution is… read more here.
Keywords: cell; nature; single cell; cell multi ... See more keywords
The Role of DOT1L in Normal and Malignant Hematopoiesis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.917125
Abstract: Disruptor of telomeric silencing 1 (DOT1) was first identified in yeast (DOT1p) and is the sole methyltransferase responsible for histone three lysine 79 (H3K79) mono-, di-, and tri-methylation. Mammalian DOT1 (DOT1-like protein or DOT1L) has… read more here.
Keywords: dot1l function; dot1l normal; dot1l; hematopoiesis ... See more keywords
The Roles of Cholesterol and Its Metabolites in Normal and Malignant Hematopoiesis
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2019.00204
Abstract: Hematopoiesis is sustained throughout life by hematopoietic stem cells (HSCs) that are capable of self-renewal and differentiation into hematopoietic progenitor cells (HPCs). There is accumulating evidence that cholesterol homeostasis is an important factor in the… read more here.
Keywords: hematopoiesis; normal malignant; cholesterol; metabolites normal ... See more keywords
PD-L2 Is Constitutively Expressed in Normal and Malignant Urothelium
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.626748
Abstract: The use of immune checkpoint blockade, in particular PD-1 and PD-L1 inhibitors, is now commonplace in many clinical settings including the treatment of muscle-invasive bladder cancer (MIBC). Notwithstanding, little information exists regarding the expression of… read more here.
Keywords: expressed normal; normal malignant; malignant urothelium; expression ... See more keywords
Role of NLRP7 in Normal and Malignant Trophoblast Cells
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10020252
Abstract: Gestational choriocarcinoma (CC) is an aggressive cancer that develops upon the occurrence of abnormal pregnancies such as Hydatidiform moles (HMs) or upon non-molar pregnancies. CC cells often metastasize in multiple organs and can cause maternal… read more here.
Keywords: role nlrp7; nlrp7 normal; trophoblast; normal malignant ... See more keywords
Autophagy and Metabolism in Normal and Malignant Hematopoiesis
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22168540
Abstract: The hematopoietic system relies on regulation of both metabolism and autophagy to maintain its homeostasis, ensuring the self-renewal and multipotent differentiation potential of hematopoietic stem cells (HSCs). HSCs display a distinct metabolic profile from that… read more here.
Keywords: autophagy metabolism; metabolism; normal malignant; differentiation ... See more keywords