Complex I and II are required for normal mitochondrial Ca2+ homeostasis.
Sign Up to like & getrecommendations! Published in 2019 at "Mitochondrion"
DOI: 10.1016/j.mito.2019.07.004
Abstract: Cytosolic calcium (cCa2+) entry into mitochondria is facilitated by the mitochondrial membrane potential (ΔΨm), an electrochemical gradient generated by the electron transport chain (ETC). Is has been assumed that as long as mutations that affect… read more here.
Keywords: homeostasis; normal mitochondrial; required normal; complex required ... See more keywords
Higher than normal mitochondrial DNA content associated with better outcome in acute promyelocytic leukaemia? Maybe
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Haematology"
DOI: 10.1111/bjh.18534
Abstract: Mitochondrial biology may influence the outcome of therapy for acute promyelocytic leukemia if arsenic trioxide is not part of the treatment. Inclusion of arsenic trioxide in the treatment regimen may cancel the adverse impact of… read more here.
Keywords: higher normal; normal mitochondrial; dna content; content associated ... See more keywords