Immunological differences between colorectal cancer and normal mucosa uncover a prognostically relevant immune cell profile
Sign Up to like & getrecommendations! Published in 2019 at "Oncoimmunology"
DOI: 10.1080/2162402x.2018.1537693
Abstract: ABSTRACT T cells in colorectal cancer (CRC) are associated with improved survival. However, checkpoint immunotherapies antagonizing the suppression of these cells are ineffective in the great majority of patients. To better understand the immune cell… read more here.
Keywords: normal mucosa; immune cell; tumor; crc ... See more keywords
Mucosal color changes on narrow-band imaging in esophageal eosinophilic infiltration
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000029891
Abstract: This study aimed to examine the range of beige colored mucosa (BCM) in patients with esophageal eosinophilic infiltration (EEI) using narrow-band imaging (NBI). In this retrospective study, EEI was confirmed histologically in 12 consecutive patients… read more here.
Keywords: esophageal eosinophilic; normal mucosa; narrow band; bcm ... See more keywords
RNA-seq Reveals Transcriptomic Differences in Inflamed and Noninflamed Intestinal Mucosa of Crohn's Disease Patients Compared with Normal Mucosa of Healthy Controls
Sign Up to like & getrecommendations! Published in 2017 at "Inflammatory Bowel Diseases"
DOI: 10.1097/mib.0000000000001066
Abstract: Background: Aberrant gene expression in the gut mucosa might contribute to the initiation and progression of Crohn's disease (CD). RNA sequencing (RNA-seq) provides precise measurements of expression levels of transcripts and their isoforms. The aim… read more here.
Keywords: transcriptomic differences; normal mucosa; expression; mucosa ... See more keywords
Gastrointestinal biopsy of normal mucosa or non-specific inflammation and risk of neurodegenerative disease: nationwide matched cohort study.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of neurology"
DOI: 10.1111/ene.15654
Abstract: BACKGROUND Evidence has accumulated to support the early involvement of altered gastrointestinal (GI) function in neurodegenerative disease. However, risk of Alzheimer's disease (AD) and Parkinson's disease (PD) among individuals with a GI biopsy of normal… read more here.
Keywords: disease; normal mucosa; non specific; specific inflammation ... See more keywords
The Regional Specificity of Mucosa-Associated Microbiota in Patients with Distal Colorectal Cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Digestion"
DOI: 10.1159/000519487
Abstract: BACKGROUND/AIMS Recent studies have demonstrated that the populations of several microbes are significantly increased in fecal samples from patients with colorectal cancer (CRC), suggesting their involvement in the development of CRC. The aim of this… read more here.
Keywords: location; colorectal cancer; normal mucosa; mucosa ... See more keywords
Long-term risk of inflammatory bowel disease after endoscopic biopsy with normal mucosa: A population-based, sibling-controlled cohort study in Sweden
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Medicine"
DOI: 10.1371/journal.pmed.1004185
Abstract: Background Although evidence suggests a persistently decreased risk of colorectal cancer for up to 10 years among individuals with a negative endoscopic biopsy result (i.e., normal mucosa), concerns have been raised about other long-term health… read more here.
Keywords: biopsy normal; normal mucosa; endoscopic biopsy; risk ... See more keywords
Differentially deregulated microRNAs as novel biomarkers for neoplastic progression in ulcerative colitis.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and translational gastroenterology"
DOI: 10.14309/ctg.0000000000000489
Abstract: BACKGROUND Colorectal cancer (CRC) is a potentially life-threatening complication of long-standing ulcerative colitis (UC). MicroRNAs are epigenetic regulators that have been involved in the development of UC associated CRC. However, their role as potential mucosal… read more here.
Keywords: neoplastic progression; biomarkers neoplastic; normal mucosa; ulcerative colitis ... See more keywords
Complete Circumferential Endoscopic Submucosal Dissection for Esophageal Cancer Leaving an Island of Normal Mucosa.
Sign Up to like & getrecommendations! Published in 2023 at "Internal medicine"
DOI: 10.2169/internalmedicine.1637-23
Abstract: Esophageal stricture caused by complete circumferential endoscopic submucosal dissection (ESD) of extensive esophageal squamous cell carcinoma (ESCC) is a major concern and can result in a low quality of life. Normal mucosa may remain within… read more here.
Keywords: complete circumferential; endoscopic submucosal; normal mucosa; leaving island ... See more keywords
DNA Methylation Signatures and the Contribution of Age-Associated Methylomic Drift to Carcinogenesis in Early-Onset Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13112589
Abstract: Simple Summary The role of DNA methylation in the carcinogenesis of colorectal cancer (CRC) diagnosed 50 years of age. CpGs that undergo ageing-related methylation drift were significantly altered in EOCRC, and accelerated ageing was also… read more here.
Keywords: drift; methylation; age; normal mucosa ... See more keywords
Efficacy of Artificial Intelligence-Assisted Discrimination of Oral Cancerous Lesions from Normal Mucosa Based on the Oral Mucosal Image: A Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14143499
Abstract: Simple Summary Early detection of oral cancer is important to increase the survival rate and reduce morbidity. For the past few years, the early detection of oral cancer using artificial intelligence (AI) technology based on… read more here.
Keywords: oral cancerous; oral cancer; normal mucosa; analysis ... See more keywords