Effects of Renal Impairment on the Pharmacokinetics of the Dual GIP and GLP-1 Receptor Agonist Tirzepatide
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Pharmacokinetics"
DOI: 10.1007/s40262-021-01012-2
Abstract: The pharmacokinetics (PK) and single-dose tolerability of tirzepatide, a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist being developed for once-weekly treatment of type 2 diabetes (T2D), weight management, and nonalcoholic steatohepatitis, was evaluated… read more here.
Keywords: receptor agonist; renal impairment; normal renal; renal function ... See more keywords
Bowman Capsule Volume and Related Factors in Adults With Normal Renal Function
Sign Up to like & getrecommendations! Published in 2018 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2017.10.007
Abstract: Introduction Alterations in glomerular filtration can considerably influence the dynamics and functions of the Bowman capsule. Despite the potentially important role in maintaining normal renal functions, few studies have focused on Bowman capsule volume in… read more here.
Keywords: capsule; normal renal; bowman capsule; renal function ... See more keywords
LDL-oxidation, serum uric acid, kidney function and pulse-wave velocity: Data from the Brisighella Heart Study cohort.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2018.03.077
Abstract: BACKGROUND Serum uric acid (SUA) and oxidized LDL (oxLDL) may be associated with arterial aging. The aim of our study was to evaluate the relationship between SUA, oxLDL and arterial stiffness in subjects with normal… read more here.
Keywords: uric acid; study; normal renal; serum uric ... See more keywords
Systematic Review and Meta analysis of Outcomes of Lower Extremity Peripheral Arterial Interventions in Patients with and without Chronic Kidney Disease or End Stage Renal Disease.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of vascular surgery"
DOI: 10.1016/j.jvs.2020.08.032
Abstract: OBJECTIVES Patients with chronic kidney disease (CKD) present with a higher risk of peripheral arterial disease (PAD). While individual studies have documented the association between CKD/ESRD and adverse outcomes in patients undergoing PAD interventions in… read more here.
Keywords: normal renal; renal function; disease; ckd esrd ... See more keywords
P1579Impact of Renal Dysfunction on Real-world Outcome of the ESC 0/1-hour Algorithm
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz748.0339
Abstract: The ESC recommends the use of a 0/1h-algorithm for rapid triage of patients with suspected non-ST-elevation myocardial infarction (NSTEMI) using high-sensitivity cardiac troponin (hs-cTn) concentrations irrespective of renal function. Patients with renal dysfunction (RD, defined… read more here.
Keywords: function; renal function; esc algorithm; normal renal ... See more keywords
Skin Toxicity After Exposure to Gadolinium-Based Contrast Agents in Normal Renal Function, Using Clinical Approved Doses: Current Status of Preclinical and Clinical Studies.
Sign Up to like & getrecommendations! Published in 2023 at "Investigative radiology"
DOI: 10.1097/rli.0000000000000973
Abstract: OBJECTIVES The aim of this study was to summarize the current preclinical and clinical evidence on the association between exposure to gadolinium (Gd) compounds and skin toxicity in a setting similar to clinical practice. MATERIALS… read more here.
Keywords: gadolinium; normal renal; gadolinium based; renal function ... See more keywords
Refractory wounds induced by normal‐renal calciphylaxis: An under‐recognised calcific arteriolopathy
Sign Up to like & getrecommendations! Published in 2022 at "International Wound Journal"
DOI: 10.1111/iwj.13951
Abstract: Normal‐renal calciphylaxis (NRC) is a devastating calcific vasculopathy characterised by refractory wounds. It is more likely to be misdiagnosed because of the absence of renal insufficiency. Failure to effectively control may lead to rapid deterioration… read more here.
Keywords: renal calciphylaxis; normal renal; refractory wounds; wounds induced ... See more keywords
Body Mass Index of Elderly Patients with Normal Renal Function as a Determining Factor for Initial Vancomycin Regimen Designing.
Sign Up to like & getrecommendations! Published in 2022 at "Chemotherapy"
DOI: 10.1159/000522455
Abstract: INTRODUCTION Currently, the use of actual body weight is recommended for dosing in vancomycin regimen designs and it is important to perform therapeutic drug monitoring for efficacy and safety. However, the method to determine the… read more here.
Keywords: renal function; patients normal; function; elderly patients ... See more keywords
The Correlation of Fibroblast Growth Factor 23 with Cardiac Remodeling in Essential Hypertension with Normal Renal Function
Sign Up to like & getrecommendations! Published in 2022 at "Cardiology"
DOI: 10.1159/000524764
Abstract: Background: Fibroblast growth factor 23 (FGF23), a glycoprotein-regulating calcium and phosphorus homeostasis, has been linked to cardiovascular diseases. We aimed to evaluate the correlation of FGF23 levels and cardiac remodeling (left atrial [LA] enlargement and… read more here.
Keywords: hypertension normal; normal renal; essential hypertension; cardiac remodeling ... See more keywords
Prediction of incident chronic kidney disease in a population with normal renal function and normo-proteinuria
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0285102
Abstract: Regarding the irreversible clinical course of chronic kidney disease, identifying high-risk subjects susceptible to Chronic Kidney Disease (CKD) has an important clinical implication. Previous studies have developed risk prediction models identifying high-risk individuals within a… read more here.
Keywords: chronic kidney; normal renal; incident; prediction ... See more keywords
＜Editors’ Choice＞ Clinical impact of standardized creatinine on dose adjustment of capecitabine
Sign Up to like & getrecommendations! Published in 2022 at "Nagoya Journal of Medical Science"
DOI: 10.18999/nagjms.84.3.547
Abstract: ABSTRACT Although the Cockcroft-Gault equation is still used for the dose adjustment of many drugs that have been approved prior to creatinine standardization, the clinical impact of standardized creatinine in the dose adjustment of capecitabine… read more here.
Keywords: function; standardized creatinine; normal renal; renal function ... See more keywords