Association of Retinoic Acid Receptor &bgr; Gene With Onset and Progression of Lichen Sclerosus–Associated Vulvar Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2018.1373
Abstract: Importance Molecular alterations in lichen sclerosus–associated vulvar squamous cell carcinoma (LS-VSCC) are largely unknown. Objective To determine whether the retinoic acid receptor &bgr; (RAR&bgr;) tumor-suppressor gene is involved in the onset and/or progression of LS-VSCC.… read more here.
Keywords: bgr; rar bgr; vscc; normal skin ... See more keywords
Monocytes co-cultured with reconstructed keloid and normal skin models skew towards M2 macrophage phenotype
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Dermatological Research"
DOI: 10.1007/s00403-019-01942-9
Abstract: Several abnormalities have been reported in the peripheral blood mononuclear cells of keloid-forming patients and particularly in the monocyte cell fraction. The goal of this in vitro study was to determine whether monocytes from keloid-prone… read more here.
Keywords: phenotype; monocytes cultured; reconstructed keloid; normal skin ... See more keywords
Dielectric and Double Debye Parameters of Artificial Normal Skin and Melanoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Infrared, Millimeter, and Terahertz Waves"
DOI: 10.1007/s10762-019-00597-x
Abstract: The aim of this study is to characterise the artificial normal skin and melanoma by testing samples with different fibroblast and metastatic melanoma cell densities using terahertz (THz) time-domain spectroscopy (TDS) attenuated total reflection (ATR)… read more here.
Keywords: melanoma samples; melanoma; skin melanoma; normal skin ... See more keywords
A comparison of proliferation levels in normal skin, physiological scar and keloid tissue.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of plastic surgery and hand surgery"
DOI: 10.1080/2000656x.2021.2017294
Abstract: Proliferation is an important characteristic of life, and many signaling pathways participate in this complicated process. The MAPK/Erk pathway is a classic pathway in cell proliferation. In this study, expression levels of key factors in… read more here.
Keywords: expression; keloid tissue; physiological scar; proliferation ... See more keywords
O017 Dupuytren's disease (DD): WNT4 knockdown in normal skin fibroblasts leads to ‘DD-like’ changes in the transcriptome
Sign Up to like & getrecommendations! Published in 2023 at "British Journal of Surgery"
DOI: 10.1093/bjs/znad101.017
Abstract: Dupuytren's disease (DD), a fibro-proliferative disorder of unknown aetiology, affects the palm and is characterised by progressive fibrosis, thickening of palmar fascia, and excess collagen deposition. Patients present with nodules, causing flexion deformity in ∼50%,… read more here.
Keywords: like changes; skin; changes transcriptome; skin fibroblasts ... See more keywords
The Role of Extracellular Matrix in Wound Healing
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DOI: 10.1097/dss.0000000000003779
Abstract: BACKGROUND Extracellular matrix communicates with surrounding cells to maintain skin homeostasis and modulate multiple cellular processes including wound healing. OBJECTIVE To elucidate the dynamic composition and potential roles of extracellular matrix in normal skin, wound… read more here.
Keywords: healing process; extracellular matrix; normal skin; wound healing ... See more keywords
Hyperspectral in vivo analysis of normal skin chromophores and visualization of oncological pathologies
Sign Up to like & getrecommendations! Published in 2019 at "Computer Optics"
DOI: 10.18287/2412-6179-2019-43-4-661-670
Abstract: In the paper, we present test results of methods for the noninvasive diagnosis of skin neoplasms, based on the hyperspectral registration of images by using a camera with an acousto-optic tunable filter. For the identification… read more here.
Keywords: oncological pathologies; hyperspectral vivo; skin; normal skin ... See more keywords
Distribution of erlotinib in rash and normal skin in cancer patients receiving erlotinib visualized by matrix assisted laser desorption/ionization mass spectrometry imaging
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.24928
Abstract: Background The development of skin rashes is the most common adverse event observed in cancer patients treated with epidermal growth factor receptor-tyrosine kinase inhibitors such as erlotinib. However, the pharmacological evidence has not been fully… read more here.
Keywords: mass spectrometry; skin; normal skin; distribution erlotinib ... See more keywords
Expression of pigment epithelium-derived factor in psoriasis, verrucae, squamous cell carcinoma and normal skin: An immunohistochemical study
Sign Up to like & getrecommendations! Published in 2020 at "Indian Journal of Dermatology, Venereology and Leprology"
DOI: 10.4103/ijdvl.ijdvl_396_19
Abstract: Background: Preservation of homeostasis status in the skin needs an equilibrium of keratinocyte proliferation, differentiation, necrosis and apoptosis. Disturbance of these regulatory mechanisms may lead to keratinocyte neoplastic and hyperproliferative diseases. Pigment epithelium-derived factor is… read more here.
Keywords: squamous cell; epithelium derived; normal skin; pigment epithelium ... See more keywords