Articles with "normal theory" as a keyword



Testing One Primary and Two Secondary Endpoints in a Two‐Stage Group Sequential Trial With Extensions

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Published in 2025 at "Statistics in Medicine"

DOI: 10.1002/sim.10346

Abstract: We study the problem of testing multiple secondary endpoints conditional on a primary endpoint being significant in a two‐stage group sequential procedure, focusing on two secondary endpoints. This extends our previous work with one secondary… read more here.

Keywords: secondary endpoints; normal theory; stage group; two secondary ... See more keywords