Normalization of clonal diversity in gene therapy studies using shape constrained splines
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DOI: 10.1038/s41598-022-05837-0
Abstract: Viral vectors are used to insert genetic material into semirandom genomic positions of hematopoietic stem cells which, after reinfusion into patients, regenerate the entire hematopoietic system. Hematopoietic cells originating from genetically modified stem cells will… read more here.
Keywords: gene therapy; gene; normalization clonal; clonal diversity ... See more keywords