Normalization strategies differently affect circulating miRNA profile associated with the training status
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-38505-x
Abstract: MicroRNAs are fine regulators of the whole-body adaptive response but their use as biomarkers is limited by the lack of standardized pre- and post-analytical procedures. This work aimed to compare different normalization approaches for RT-qPCR… read more here.
Keywords: status; circulating mirna; normalization strategies; different normalization ... See more keywords
Comparison of Data Normalization Strategies for Array-Based MicroRNA Profiling Experiments and Identification and Validation of Circulating MicroRNAs as Endogenous Controls in Hypertension
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.836636
Abstract: Introduction: MicroRNAs are small noncoding RNAs with potential regulatory roles in hypertension and drug response. The presence of many of these RNAs in biofluids has spurred investigation into their role as possible biomarkers for use… read more here.
Keywords: normalization strategies; hypertension; control; array based ... See more keywords
What is Normalization? The Strategies Employed in Top-Down and Bottom-Up Proteome Analysis Workflows
Sign Up to like & getrecommendations! Published in 2019 at "Proteomes"
DOI: 10.3390/proteomes7030029
Abstract: The accurate quantification of changes in the abundance of proteins is one of the main applications of proteomics. The maintenance of accuracy can be affected by bias and error that can occur at many points… read more here.
Keywords: analysis; top bottom; employed top; normalization strategies ... See more keywords