Renal Arterial Anatomy: Implications for Normothermic Machine Perfusion in Renal Transplantation.
Sign Up to like & getrecommendations! Published in 2025 at "Clinical anatomy"
DOI: 10.1002/ca.24286
Abstract: Normothermic machine perfusion (NMP) is a novel technology that has shown potential in viability assessment and reconditioning of donor organs. Normothermic machine perfusion is technically more challenging in kidneys with multiple renal arteries (RAs). This… read more here.
Keywords: normothermic machine; machine perfusion; group; perfusion ... See more keywords
Letter to Editor: Repair or Prevent: What Is the Real Impact of Normothermic Machine Perfusion in Liver Transplantation?
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30567
Abstract: We read with great interest the paper by Jassem et al(1), which provides detailed gene expression profiles of human livers during normothermic machine perfusion (NMP), compared to conventional cold storage. Authors should be congratulated to… read more here.
Keywords: machine perfusion; letter editor; editor repair; normothermic machine ... See more keywords
Normothermic Machine Perfusion of Explanted Human Metabolic Livers: A Proof of Concept for Studying Inborn Errors of Metabolism
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DOI: 10.1002/jimd.70010
Abstract: The human liver plays a central metabolic role; however, its physiology may become imbalanced in inborn errors of metabolism (IEM), a broad category of monogenic disorders. Liver transplantation has been increasingly used to improve patient… read more here.
Keywords: inborn errors; machine perfusion; normothermic machine; errors metabolism ... See more keywords
Manipulation of Lipid Metabolism During Normothermic Machine Perfusion: Effect of Defatting Therapies on Donor Liver Functional Recovery
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DOI: 10.1002/lt.25439
Abstract: Strategies to increase the use of steatotic donor livers are required to tackle the mortality on the transplant waiting list. We aimed to test the efficacy of pharmacological enhancement of the lipid metabolism of human… read more here.
Keywords: metabolism; normothermic machine; functional recovery; machine perfusion ... See more keywords
Normothermic Machine Perfusion in Liver Transplantation: Feasibility and Promise of Avoiding Recooling Before Engrafting
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DOI: 10.1002/lt.25473
Abstract: It is well known that ischemia and the reperfusion process are distinct nonimmunological events that negatively impact graft outcome and induce delayed graft function, which are associated with high rates of organ failure, retransplantation, and… read more here.
Keywords: normothermic machine; transplantation feasibility; transplantation; liver transplantation ... See more keywords
Assessment of hemodynamic and blood parameters that may reflect macroscopic quality of porcine kidneys during normothermic machine perfusion using whole blood
Sign Up to like & getrecommendations! Published in 2024 at "World Journal of Urology"
DOI: 10.1007/s00345-024-05139-2
Abstract: Purpose Using ex vivo normothermic machine perfusion (NMP) with whole blood we assessed marginal porcine kidneys under reperfusion. The aim was to link measureable machine and clinical blood parameters with the currently used visual assessment.… read more here.
Keywords: normothermic machine; machine perfusion; whole blood; macroscopic ... See more keywords
Current review of machine perfusion in liver transplantation from the Japanese perspective
Sign Up to like & getrecommendations! Published in 2021 at "Surgery Today"
DOI: 10.1007/s00595-021-02265-x
Abstract: In light of the present evidence, machine perfusion is opening up new horizons in the field of liver transplantation. Although many advances have been made in liver transplantation, organ preservation methods have so far changed… read more here.
Keywords: normothermic machine; machine perfusion; liver transplantation; perfusion ... See more keywords
Liver transplantation with a normothermic machine preserved fatty nonagenarian liver: A case report
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Surgery Case Reports"
DOI: 10.1016/j.ijscr.2019.03.033
Abstract: Highlights • The ex-situ normothermic machine perfusion provide a successful recondition of nonagenarian liver.• Gentle cannulation of hepatic artery is mandatory in order to avoid unwanted intimal damage.• In order to minimise post LT hepatic… read more here.
Keywords: nonagenarian liver; liver transplantation; case; normothermic machine ... See more keywords
Dealing With Liver Transplantation during Coronavirus Disease 2019 Pandemic: Normothermic Machine Perfusion Enables for Donor, Organ, and Recipient Assessment: A Case Report
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DOI: 10.1016/j.transproceed.2020.07.011
Abstract: Abstract The SARS-CoV-2 pandemic has changed life on a global scale. The numbers in transplantation have plumped in fear of disease transmission, recipient Covid-19 infection, priority shift and resource limitations. Covid-19 complicates transplantation since donor… read more here.
Keywords: machine perfusion; transplantation; recipient; normothermic machine ... See more keywords
A proof-of-concept study in small and large animal models for coupling liver normothermic machine perfusion with mesenchymal stromal cell bioreactors
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DOI: 10.1038/s41467-024-55217-7
Abstract: To fully harness mesenchymal-stromal-cells (MSCs)’ benefits during Normothermic Machine Perfusion (NMP), we developed an advanced NMP platform coupled with a MSC-bioreactor and investigated its bio-molecular effects and clinical feasibility using rat and porcine models. The… read more here.
Keywords: normothermic machine; machine perfusion; machine; mesenchymal stromal ... See more keywords
Pharmacologic targeting of renal ischemia-reperfusion injury using a normothermic machine perfusion platform
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DOI: 10.1038/s41598-020-63687-0
Abstract: Normothermic machine perfusion (NMP) is an emerging modality for kidney preservation prior to transplantation. NMP may allow directed pharmacomodulation of renal ischemia-reperfusion injury (IRI) without the need for systemic donor/recipient therapies. Three proven anti-IRI agents… read more here.
Keywords: renal ischemia; perfusion; normothermic machine; iri ... See more keywords