Letter to Editor: Repair or Prevent: What Is the Real Impact of Normothermic Machine Perfusion in Liver Transplantation?
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30567
Abstract: We read with great interest the paper by Jassem et al(1), which provides detailed gene expression profiles of human livers during normothermic machine perfusion (NMP), compared to conventional cold storage. Authors should be congratulated to… read more here.
Keywords: machine perfusion; letter editor; editor repair; normothermic machine ... See more keywords
Manipulation of Lipid Metabolism During Normothermic Machine Perfusion: Effect of Defatting Therapies on Donor Liver Functional Recovery
Sign Up to like & getrecommendations! Published in 2019 at "Liver Transplantation"
DOI: 10.1002/lt.25439
Abstract: Strategies to increase the use of steatotic donor livers are required to tackle the mortality on the transplant waiting list. We aimed to test the efficacy of pharmacological enhancement of the lipid metabolism of human… read more here.
Keywords: metabolism; normothermic machine; functional recovery; machine perfusion ... See more keywords
Normothermic Machine Perfusion in Liver Transplantation: Feasibility and Promise of Avoiding Recooling Before Engrafting
Sign Up to like & getrecommendations! Published in 2019 at "Liver Transplantation"
DOI: 10.1002/lt.25473
Abstract: It is well known that ischemia and the reperfusion process are distinct nonimmunological events that negatively impact graft outcome and induce delayed graft function, which are associated with high rates of organ failure, retransplantation, and… read more here.
Keywords: normothermic machine; transplantation feasibility; transplantation; liver transplantation ... See more keywords
Current review of machine perfusion in liver transplantation from the Japanese perspective
Sign Up to like & getrecommendations! Published in 2021 at "Surgery Today"
DOI: 10.1007/s00595-021-02265-x
Abstract: In light of the present evidence, machine perfusion is opening up new horizons in the field of liver transplantation. Although many advances have been made in liver transplantation, organ preservation methods have so far changed… read more here.
Keywords: normothermic machine; machine perfusion; liver transplantation; perfusion ... See more keywords
Liver transplantation with a normothermic machine preserved fatty nonagenarian liver: A case report
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Surgery Case Reports"
DOI: 10.1016/j.ijscr.2019.03.033
Abstract: Highlights • The ex-situ normothermic machine perfusion provide a successful recondition of nonagenarian liver.• Gentle cannulation of hepatic artery is mandatory in order to avoid unwanted intimal damage.• In order to minimise post LT hepatic… read more here.
Keywords: nonagenarian liver; liver transplantation; case; normothermic machine ... See more keywords
Dealing With Liver Transplantation during Coronavirus Disease 2019 Pandemic: Normothermic Machine Perfusion Enables for Donor, Organ, and Recipient Assessment: A Case Report
Sign Up to like & getrecommendations! Published in 2020 at "Transplantation Proceedings"
DOI: 10.1016/j.transproceed.2020.07.011
Abstract: Abstract The SARS-CoV-2 pandemic has changed life on a global scale. The numbers in transplantation have plumped in fear of disease transmission, recipient Covid-19 infection, priority shift and resource limitations. Covid-19 complicates transplantation since donor… read more here.
Keywords: machine perfusion; transplantation; recipient; normothermic machine ... See more keywords
Pharmacologic targeting of renal ischemia-reperfusion injury using a normothermic machine perfusion platform
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-63687-0
Abstract: Normothermic machine perfusion (NMP) is an emerging modality for kidney preservation prior to transplantation. NMP may allow directed pharmacomodulation of renal ischemia-reperfusion injury (IRI) without the need for systemic donor/recipient therapies. Three proven anti-IRI agents… read more here.
Keywords: renal ischemia; perfusion; normothermic machine; iri ... See more keywords
The effect of blood cells retained in rat livers during static cold storage on viability outcomes during normothermic machine perfusion
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-02417-6
Abstract: In transplantation, livers are transported to recipients using static cold storage (SCS), whereby livers are exposed to cold ischemic injury that contribute to post-transplant risk factors. We hypothesized that flushing organs during procurement with cold… read more here.
Keywords: rat livers; cold storage; normothermic machine; static cold ... See more keywords
A proof of concept study on real-time LiMAx CYP1A2 liver function assessment of donor grafts during normothermic machine perfusion
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-02641-0
Abstract: No single reliable parameter exists to assess liver graft function of extended criteria donors during ex-vivo normothermic machine perfusion (NMP). The liver maximum capacity (LiMAx) test is a clinically validated cytochromal breath test, measuring liver… read more here.
Keywords: liver function; limax; function; normothermic machine ... See more keywords
Normothermic machine perfusion of the kidney
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Organ Transplantation"
DOI: 10.1097/mot.0000000000000470
Abstract: Purpose of review Normothermic machine perfusion (NMP) is a preservation method that is generating increasing interest. The aim of this review is to summarise the current status of NMP in regards of kidney viability assessment,… read more here.
Keywords: perfusion; perfusion kidney; normothermic machine; machine perfusion ... See more keywords
Normothermic machine perfusion of kidneys: current strategies and future perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Organ Transplantation"
DOI: 10.1097/mot.0000000000001003
Abstract: Purpose of review This review aims to summarize the latest original preclinical and clinical articles in the setting of normothermic machine perfusion (NMP) of kidney grafts. Recent findings Kidney NMP can be safely translated into… read more here.
Keywords: normothermic machine; kidney; machine perfusion; perfusion ... See more keywords