Regulation of Notch signaling in the developing Drosophila eye by a T‐box containing transcription factor, Dorsocross
Sign Up to like & getrecommendations! Published in 2018 at "genesis"
DOI: 10.1002/dvg.23251
Abstract: Owing to a multitude of functions, there is barely a tissue or a cellular process that is not being regulated by Notch signaling. To allow the Notch signal to be deployed in numerous contexts, many… read more here.
Keywords: notch; eye discs; genetic interaction; notch signaling ... See more keywords
Pharmacological inhibition of the Notch pathway enhances the efficacy of androgen deprivation therapy for prostate cancer
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31346
Abstract: Although androgen deprivation therapy (ADT) is a standard treatment for metastatic prostate cancer, this disease inevitably recurs and progresses to ADT‐resistant stage after this therapy. Accordingly, understanding the mechanism of resistance to ADT and finding… read more here.
Keywords: notch; inhibition notch; notch pathway; therapy ... See more keywords
TGFβ signaling controls intrahepatic bile duct development may through regulating the Jagged1‐Notch‐Sox9 signaling axis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26304
Abstract: Due to the inherent limitations of the mouse models, the molecular mechanism of TGFβ signaling involved in the development of intrahepatic bile ducts (IHBDs) has been investigated little. Here, we investigated the role of TGFβ… read more here.
Keywords: tgf signaling; notch; tgf; sox9 ... See more keywords
Notch signaling at the crossroads of innate and adaptive immunity
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.1ri0520-138r
Abstract: Notch signaling is an evolutionarily conserved cell‐to‐cell signaling pathway that regulates cellular differentiation and function across multiple tissue types and developmental stages. In this review, we discuss our current understanding of Notch signaling in mammalian… read more here.
Keywords: notch; innate adaptive; adaptive immunity; notch signaling ... See more keywords
Stub loaded, low profile UWB antenna with independently controllable notch‐bands
Sign Up to like & getrecommendations! Published in 2019 at "Microwave and Optical Technology Letters"
DOI: 10.1002/mop.31915
Abstract: The design and realization of a compact coplanar waveguide (CPW) fed ultrawideband (UWB) antenna having dual‐notched bands is presented in this article. The antenna possesses on demand notch bands at 4 to 5.78 GHz and 6.83… read more here.
Keywords: uwb antenna; notch bands; notch; controllable notch ... See more keywords
UWB monopole antenna with dual‐band‐notched characteristics
Sign Up to like & getrecommendations! Published in 2019 at "Microwave and Optical Technology Letters"
DOI: 10.1002/mop.32112
Abstract: A UWB planar monopole antenna with dual‐band notch characteristics is presented in this paper. Measured results show that the proposed antenna operates with a 2.76 to 11 GHz 10 dB return loss bandwidth with notch bands covering… read more here.
Keywords: antenna; notch; antenna dual; band ... See more keywords
Canonical Notch signaling is required for bone morphogenetic protein‐mediated human osteoblast differentiation
Sign Up to like & getrecommendations! Published in 2020 at "STEM CELLS"
DOI: 10.1002/stem.3245
Abstract: Osteoblast differentiation of bone marrow‐derived human mesenchymal stem cells (hMSC) can be induced by stimulation with canonical Notch ligand, Jagged1, or bone morphogenetic proteins (BMPs). However, it remains elusive how these two pathways lead to… read more here.
Keywords: protein; notch; differentiation; osteoblast differentiation ... See more keywords
Lenvatinib induces cardiac developmental toxicity in zebrafish embryos through regulation of Notch mediated-oxidative stress generation.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental toxicology"
DOI: 10.1002/tox.23485
Abstract: Due to an increasing number of abused drugs dumped into the wastewater, more and more drugs are detected in the water environment, which may affect the survival of aquatic organisms. Lenvatinib is a multi-targeted tyrosine… read more here.
Keywords: cardiac developmental; notch; stress; zebrafish embryos ... See more keywords
Role of Notch Signaling in Leg Development in Drosophila melanogaster.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-34436-8_7
Abstract: Notch pathway plays diverse and fundamental roles during animal development. One of the most relevant, which arises directly from its unique mode of activation, is the specification of cell fates and tissue boundaries. The development… read more here.
Keywords: notch; role notch; drosophila melanogaster; leg development ... See more keywords
NOTCH and Esophageal Squamous Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-55031-8_5
Abstract: Esophageal squamous cell carcinoma (ESCC) is a deadly disease that requires extensive research on its mechanisms, prevention, and therapy. Recent studies have shown that NOTCH mutations are commonly seen in human ESCC. This chapter summarizes… read more here.
Keywords: cell carcinoma; squamous cell; notch; notch pathway ... See more keywords
Truncated-pyramid shape simulation for the measurement of femoral intercondylar notch volume can detect the volume difference between ACL-injured and intact subjects
Sign Up to like & getrecommendations! Published in 2020 at "Knee Surgery, Sports Traumatology, Arthroscopy"
DOI: 10.1007/s00167-020-06204-0
Abstract: The purpose of this study was to measure the femoral intercondylar notch volume using a truncated-pyramid shape simulation and compare this volume between anterior cruciate ligament (ACL) injured and intact subjects. Forty-seven subjects diagnosed with… read more here.
Keywords: acl injured; volume; notch; intercondylar notch ... See more keywords