Intracellular trafficking of Notch orchestrates temporal dynamics of Notch activity in the fly brain
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-22442-3
Abstract: While Delta non-autonomously activates Notch in neighboring cells, it autonomously inactivates Notch through cis-inhibition, the molecular mechanism and biological roles of which remain elusive. The wave of differentiation in the Drosophila brain, the ‘proneural wave’,… read more here.
Keywords: notch orchestrates; trafficking notch; notch; notch activity ... See more keywords
Notch activity mediates oestrogen-induced stromal cell invasion in endometriosis.
Sign Up to like & getrecommendations! Published in 2018 at "Reproduction"
DOI: 10.1530/rep-18-0326
Abstract: Oestrogen has been reported to control the invasiveness of endometrial stromal cells in endometriosis. Notch signalling, a master regulator of cell invasion in tumours, is regulated by oestrogen in other diseases and hyperactivated in endometriotic… read more here.
Keywords: notch activity; oestrogen; cell; cell invasion ... See more keywords