Cadmium modulates steatosis, fibrosis, and oncogenic signaling in liver cancer cells by activating notch and AKT/mTOR pathways
Sign Up to like & getrecommendations! Published in 2023 at "Environmental Toxicology"
DOI: 10.1002/tox.23731
Abstract: Cadmium (Cd) is an environmental pollutant that increases hepatotoxicity and the risk of liver diseases. In the current study, we investigated the effect of a physiologically relevant, low concentration of Cd on the regulation of… read more here.
Keywords: liver; akt mtor; oncogenic signaling; notch akt ... See more keywords
MicroRNA-223-induced inhibition of the FBXW7 gene affects the proliferation and apoptosis of colorectal cancer cells via the Notch and Akt/mTOR pathways
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2020.11793
Abstract: The tumour suppressor gene F-box and WD repeat domain-containing 7 (FBXW7) plays an important role in human cancer by regulating cell division, proliferation and differentiation. However, the exact regulatory mechanisms of microRNA (miR)-223 in colorectal… read more here.
Keywords: apoptosis; proliferation apoptosis; notch akt; mir 223 ... See more keywords