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Notch1 Deficiency Induces Tumor Cell Accumulation Inside the Bronchiolar Lumen and Increases TAZ Expression in an Autochthonous Kras LSL-G12V Driven Lung Cancer Mouse Model

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Published in 2021 at "Pathology and Oncology Research"

DOI: 10.3389/pore.2021.596522

Abstract: Purpose: Abrogation of Notch signaling, which is pivotal for lung development and pulmonary epithelial cell fate decisions was shown to be involved in the aggressiveness and the differentiation of lung carcinomas. Additionally, the transcription factors… read more here.

Keywords: notch1 deficiency; taz expression; cancer; cell ... See more keywords