The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL
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DOI: 10.1182/blood-2018-99-118827
Abstract: Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer with a cumulative risk of ~1 in 2,000 children by the age of 15 years and an increasing incidence over the last 30 years.Whilst advances… read more here.
Keywords: notch1 driven; figure; vulnerability notch1; ros levels ... See more keywords