Notch2 controls developmental fate choices between germinal center and marginal zone B cells upon immunization
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-46024-1
Abstract: Sustained Notch2 signals induce trans-differentiation of Follicular B (FoB) cells into Marginal Zone B (MZB) cells in mice, but the physiology underlying this differentiation pathway is still elusive. Here, we demonstrate that most B cells… read more here.
Keywords: mzb cells; zone cells; marginal zone; notch2 signaling ... See more keywords
Notch1 and Notch2 Signaling Exclusively but Cooperatively Maintain Fetal Myogenic Progenitors.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cells"
DOI: 10.1093/stmcls/sxac056
Abstract: Myogenic progenitors (MPs) generate myocytes that fuse to form myofibers during skeletal muscle development while maintaining the progenitor pool, which is crucial for generating sufficient muscle. Notch signaling has been known to reserve a population… read more here.
Keywords: notch1 notch2; cooperatively maintain; notch2 signaling; signaling exclusively ... See more keywords