PO-393 Notch3 and CXCR4 cross-signalling sustains acute T-cell leukaemia progression
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DOI: 10.1136/esmoopen-2018-eacr25.905
Abstract: Introduction Acute T-cell lymphoblastic leukaemia (T-ALL) is a childhood cancer, characterised by infiltration of immature T-cells in bone marrow. Notch hyperactivation is a major driver of T-ALL development where CXCL12/CXCR4 axis plays an important role… read more here.
Keywords: notch3 cxcr4; acute cell; expression cxcr4; cell ... See more keywords