Active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model
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DOI: 10.15252/emmm.202216556
Abstract: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic form of familial small vessel disease and no preventive or curative therapy is available. CADASIL is caused by mutations in… read more here.
Keywords: active immunotherapy; brain capillaries; notch3 deposition; cadasil ... See more keywords