The novel activity of Argonautes in intron splicing: A transcriptome-wide survey in plants.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of plant physiology"
DOI: 10.1016/j.jplph.2022.153632
Abstract: The importance of the evolutionarily conserved Argonaute (AGO) proteins has been well recognized for their involvement in the RNA interference pathways. Recent discoveries in animals demonstrated that AGOs also participate in alternative splicing (AS). Motivated… read more here.
Keywords: ago proteins; intron splicing; activity argonautes; novel activity ... See more keywords
3-pyridyl inhibitors with novel activity against Trypanosoma cruzi reveal in vitro profiles can aid prediction of putative cytochrome P450 inhibition
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-22043-z
Abstract: Using high throughput, high-content imaging, a proprietary library was screened against intracellular Trypanosoma cruzi amastigotes to identify compounds with novel activity against the parasite. Five inhibitors were discovered, which did not clear all of the… read more here.
Keywords: novel activity; activity; cruzi; cytochrome p450 ... See more keywords