Design, synthesis, conformational and molecular docking study of some novel acyl hydrazone based molecular hybrids as antimalarial and antimicrobial agents
Sign Up to like & getrecommendations! Published in 2017 at "Chemistry Central Journal"
DOI: 10.1186/s13065-017-0344-7
Abstract: BackgroundAcyl hydrazones are an important class of heterocyclic compounds promising pharmacological characteristics. Malaria is a life-threatening mosquito-borne blood disease caused by a plasmodium parasite. In some places, malaria can be treated and controlled with early… read more here.
Keywords: novel acyl; design synthesis; hydrazone based; acyl hydrazone ... See more keywords
Synthesis and Characterization of Novel 2-Acyl-3-trifluoromethylquinoxaline 1,4-Dioxides as Potential Antimicrobial Agents
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15020155
Abstract: The emergence of drug resistance in pathogens leads to a loss of effectiveness of antimicrobials and complicates the treatment of bacterial infections. Quinoxaline 1,4-dioxides represent a prospective scaffold for search of new compounds with improved… read more here.
Keywords: acyl trifluoromethylquinoxaline; trifluoromethylquinoxaline dioxides; novel acyl; quinoxaline dioxides ... See more keywords