SYNTHESIS, STRUCTURE, AND ANTIVIRAL PROPERTIES OF NOVEL 2-ADAMANTYL-5-ARYL-2 H -TETRAZOLES
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DOI: 10.1007/6073
Abstract: The reaction of 5-aryl- NH -tetrazoles with adamantan-1-ol in concentrated sulfuric acid proceeds regioselectively with the formation of the corresponding 2-adamantyl-5-aryl-2 H -tetrazoles. Nitration of these compounds leads to 2-(adamantan-1-yl)-5-(3-nitroaryl)-2 H -tetrazoles. The structures and… read more here.
Keywords: novel adamantyl; adamantyl aryl; spectroscopy; synthesis structure ... See more keywords
In vitro antiproliferative study of novel adamantyl pyridin-4-ones
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DOI: 10.1007/s11030-017-9763-6
Abstract: The preparation of several N-aryl-substituted (phenyl, p-methylphenyl, p-methoxyphenyl, p-nitrophenyl, p-aminophenyl, p-hydroxyphenyl) 3-hydroxy-2-methylpyridin-4-ones as well as their adamantyl derivatives is described, and their in vitro antitumor properties were investigated. The compounds were synthesized in good yields… read more here.
Keywords: study novel; novel adamantyl; study; antiproliferative study ... See more keywords
Novel adamantyl clubbed iminothiazolidinones as promising elastase inhibitors: design, synthesis, molecular docking, ADMET and DFT studies
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DOI: 10.1039/d1ra09318e
Abstract: Porcine Pancreatic Elastase (PPE) is a serine protease that is homologous to trypsin and chymotrypsin that are involved in various pathologies like inflammatory disease, Chronic Obstructive Pulmonary Disease (COPD), acute respiratory distress syndrome, cystic fibrosis,… read more here.
Keywords: molecular docking; dft studies; elastase; novel adamantyl ... See more keywords