A novel ADPKD model using kidney organoids derived from disease-specific human iPSCs.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.06.141
Abstract: Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disorder which manifests progressive renal cyst formation and leads to end-stage kidney disease. Around 85% of cases are caused by PKD1 heterozygous mutations, exhibiting relatively poorer… read more here.
Keywords: novel adpkd; kidney organoids; adpkd model; disease ... See more keywords