Discovery and characterization of potent IL-21 neutralizing antibodies via a novel alternating antigen immunization and humanization strategy
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DOI: 10.1371/journal.pone.0211236
Abstract: Interleukin-21 (IL-21), a member of the common cytokine receptor γ chain (γc) family, is secreted by CD4+ T cells and natural killer T cells and induces effector function through interactions with the IL-21 receptor (IL-21R)/γc… read more here.
Keywords: immunization; novel alternating; potent neutralizing; neutralizing antibodies ... See more keywords