A Novel Animal Model for Studying Depression Featuring the Induction of the Unfolded Protein Response in Hippocampus
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Neurobiology"
DOI: 10.1007/s12035-019-01687-6
Abstract: Depression is the leading cause of disability worldwide with global distribution of 322 million people suffering from the disease. While much is understood about depression, the underlying pathophysiology is yet to be fully characterized. Recently,… read more here.
Keywords: depression; response; unfolded protein; protein response ... See more keywords
Effect of a novel animal milk oligosaccharide biosimilar on macronutrient digestibility and gastrointestinal tolerance, fecal metabolites, and fecal microbiota of healthy adult cats.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of animal science"
DOI: 10.1093/jas/skaa399
Abstract: GNU100 is a novel animal milk oligosaccharide (AMO) biosimilar. In a recent in vitro fermentation study, GNU100 was shown to be fermentable by feline gastrointestinal microbiota and lead to increased short-chain fatty acid production. Our… read more here.
Keywords: novel animal; gnu100; adult cats; cats fed ... See more keywords
SP0003 Novel animal model in arthritis
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.7154
Abstract: We have generated two rheumatoid arthritis (RA) models, human T-cell leukemia virus type I (HTLV-I) transgenic mice and IL-1 receptor antagonist (Ra)-deficient (KO) mice, to elucidate the pathogenic mechanisms of the disease. Both models spontaneously… read more here.
Keywords: dcir mice; sp0003 novel; model; mice ... See more keywords
Dental pulp-derived stem cell conditioned medium to regenerate peripheral nerves in a novel animal model of dysphagia
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0208938
Abstract: In nerve regeneration studies, various animal models are used to assess nerve regeneration. However, because of the difficulties in functional nerve assessment, a visceral nerve injury model is yet to be established. The superior laryngeal… read more here.
Keywords: animal model; model; novel animal; stem ... See more keywords
miR‐33 in cardiometabolic diseases: lessons learned from novel animal models and approaches
Sign Up to like & getrecommendations! Published in 2021 at "EMBO Molecular Medicine"
DOI: 10.15252/emmm.202012606
Abstract: miRNAs have emerged as critical regulators of nearly all biologic processes and important therapeutic targets for numerous diseases. However, despite the tremendous progress that has been made in this field, many misconceptions remain among much… read more here.
Keywords: diseases lessons; mir cardiometabolic; cardiometabolic diseases; lessons learned ... See more keywords