Novel antibacterial polysaccharides produced by endophyte Fusarium solani DO7.
Sign Up to like & getrecommendations! Published in 2019 at "Bioresource technology"
DOI: 10.1016/j.biortech.2019.121596
Abstract: In this study, the primary antibacterial ingredients in Fusarium solani DO7 were confirmed as polysaccharides. After purification, two polysaccharides, DY1 and DY2, exhibited excellent antibacterial activity, especially to S. aureus and E. coli. Moreover, the… read more here.
Keywords: novel antibacterial; dy1 dy2; solani do7; fusarium solani ... See more keywords
Phage-based target discovery and its exploitation towards novel antibacterial molecules.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2020.08.015
Abstract: The deeply intertwined evolutionary history between bacteriophages and bacteria has endowed phages with highly specific mechanisms to hijack bacterial cell metabolism for their propagation. Here, we present a comprehensive, phage-driven strategy to reveal novel antibacterial… read more here.
Keywords: novel antibacterial; discovery exploitation; based target; phage ... See more keywords
Lipophilic efficient phenylthiazoles with potent undecaprenyl pyrophosphatase inhibitory activity.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.04.063
Abstract: Antibiotic resistance remains a pressing medical challenge for which novel antibacterial agents are urgently needed. The phenylthiazole scaffold represents a promising platform to develop novel antibacterial agents for drug-resistant infections. However, enhancing the physicochemical profile… read more here.
Keywords: novel antibacterial; lipophilic efficient; antibacterial agents; undecaprenyl pyrophosphatase ... See more keywords
Novel antibacterial cellulose acetate fibers modified with 2-fluoropyridine complexes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.127537
Abstract: Abstract The complexes represented with the general formula [ML2Cl2] (L: 2-fluoropyridine; M: Ni (II), Cu (II), Co (II)) were synthesized and their structures were characterized via FT-IR and 1H NMR techniques. Thermal properties of the… read more here.
Keywords: novel antibacterial; fluoropyridine; antibacterial cellulose; fibers modified ... See more keywords
Predicting novel antibacterial agents
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Drug Discovery"
DOI: 10.1038/d41573-020-00033-z
Abstract: Discovering new antibiotics capable of tackling resistant bacteria is increasingly difficult. Stokes et al. train a deep neural network model to predict molecules with antibacterial activity. Applying the model to the Drug Repurposing Hub identified… read more here.
Keywords: novel antibacterial; antibacterial agents; predicting novel;
Synthesis of novel antibacterial and antifungal quinoxaline derivatives
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d1ra07559d
Abstract: A series of quinoxaline derivatives were designed, synthesized and evaluated as antimicrobial agents against plant pathogenic bacteria and fungi. Some of these compounds exhibited significant antibacterial and antifungal activities in vitro. Compound 5k displayed good… read more here.
Keywords: quinoxaline derivatives; novel antibacterial; antibacterial antifungal; antifungal quinoxaline ... See more keywords
Novel Antibacterial Compounds and their Drug Targets - Successes and Challenges.
Sign Up to like & getrecommendations! Published in 2017 at "Current medicinal chemistry"
DOI: 10.2174/0929867323666161213102127
Abstract: Infectious diseases are one of the most important and urgent health problems in the world. According to the World Health Organization (WHO) statistics, infectious and parasitic diseases are a cause of about 16% of all… read more here.
Keywords: novel antibacterial; drug targets; antibacterial drugs; infectious diseases ... See more keywords
Novel Antibacterial Metals as Food Contact Materials: A Review
Sign Up to like & getrecommendations! Published in 2023 at "Materials"
DOI: 10.3390/ma16083029
Abstract: Food contamination caused by microorganisms is a significant issue in the food field that not only affects the shelf life of food, but also threatens human health, causing huge economic losses. Considering that the materials… read more here.
Keywords: food; contact; novel antibacterial; food contact ... See more keywords
Selenocompounds as Novel Antibacterial Agents and Bacterial Efflux Pump Inhibitors
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24081487
Abstract: Bacterial multidrug resistance is becoming a growing problem for public health, due to the development and spreading of bacterial strains resistant to antimicrobials. In this study, the antibacterial and multidrug resistance reversing activity of a… read more here.
Keywords: novel antibacterial; selenocompounds novel; efflux pump; antibacterial agents ... See more keywords
Special Issue “Novel Antibacterial Agents”
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DOI: 10.3390/ph14040382
Abstract: This Special Issue of Pharmaceuticals is devoted to significant advances achieved in the field of antibacterial agents [...]. read more here.
Keywords: novel antibacterial; special issue; antibacterial agents; issue novel ... See more keywords