Fostering R&D of novel antibiotics and other technologies to prevent and treat infection
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DOI: 10.1093/eurpub/ckaa165.1203
Abstract: Generating innovative antibiotics is an essential part of addressing antimicrobial resistance. New policies and incentives are necessary to overcoming the multiplicity of scientific, regulatory, and economic hurdles that obstruct antibiotic discovery and development. This presentation… read more here.
Keywords: prevent treat; antibiotics technologies; technologies prevent; development ... See more keywords
Mining for novel antibiotics in the age of antimicrobial resistance
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DOI: 10.1111/1751-7915.13662
Abstract: The misuse of antimicrobials is causing an alarming increase in the appearance of antibiotic‐resistant microorganisms. In this context, the identification of novel antibiotics against new targets and with low rates of resistance development is a… read more here.
Keywords: age antimicrobial; antibiotics age; mining novel; antimicrobial resistance ... See more keywords
Drug Regimens of Novel Antibiotics in Critically Ill Patients with Varying Renal Functions: A Rapid Review
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DOI: 10.3390/antibiotics11050546
Abstract: There is currently an increase in the emergence of multidrug-resistant bacteria (MDR) worldwide, requiring the development of novel antibiotics. However, it is not only the choice of antibiotic that is important in treating an infection;… read more here.
Keywords: ill patients; regimens novel; critically ill; novel antibiotics ... See more keywords
Deep Transfer Learning Enables Robust Prediction of Antimicrobial Resistance for Novel Antibiotics
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DOI: 10.3390/antibiotics11111611
Abstract: Antimicrobial resistance (AMR) has become one of the serious global health problems, threatening the effective treatment of a growing number of infections. Machine learning and deep learning show great potential in rapid and accurate AMR… read more here.
Keywords: transfer learning; antimicrobial resistance; novel antibiotics; deep transfer ... See more keywords
Antibiotic-Resistant Bacteria and the Use of Novel Antibiotics in Children.
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DOI: 10.3928/19382359-20180807-01
Abstract: Infections due to antibiotic-resistant bacteria in children are on the rise worldwide. Treating these infections is a challenge for pediatric caregivers. In this arms race, the armamentarium of antibiotics is quickly being depleted. This article… read more here.
Keywords: antibiotics children; use novel; bacteria use; antibiotic resistant ... See more keywords