Novel Antimicrobials for the Treatment of Clostridium difficile Infection
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2018.00096
Abstract: The current picture of Clostridium difficile infection (CDI) is alarming with a mortality rate ranging between 3% and 15% and a CDI recurrence rate ranging from 12% to 40%. Despite the great efforts made over… read more here.
Keywords: clostridium difficile; novel antimicrobials; cdi; difficile infection ... See more keywords
1,4-Dihydropyridine as a Promising Scaffold for Novel Antimicrobials Against Helicobacter pylori
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.874709
Abstract: The increasing occurrence of multidrug-resistant strains of the gastric carcinogenic bacterium Helicobacter pylori threatens the efficacy of current eradication therapies. In a previous work, we found that several 1,4-dihydropyridine (DHP)-based antihypertensive drugs exhibited strong bactericidal… read more here.
Keywords: antimicrobials helicobacter; scaffold novel; promising scaffold; dihydropyridine promising ... See more keywords